Evidence map›Paper›PMID 32655711›Full record

ArticleCognitive neurodynamics2020

Medium- and long-term functional behavior evaluations in an experimental focal ischemic stroke mouse model.

Juçara Loli de Oliveira, Marina Ávila, Thiago Cesar Martins, Marcio Alvarez-Silva, Elisa Cristiana Winkelmann-Duarte, Afonso Shiguemi Inoue Salgado, Francisco José Cidral-Filho, William R Reed, Daniel F Martins

Open access · greenAbstract read
In one paragraph

Article in Cognitive neurodynamics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Juçara Loli de OliveiraDepartment of Morphological Sciences, Federal University of Santa Catarina, Santa Catarina, Brazil.
Marina ÁvilaExperimental Neuroscience Laboratory (LaNEx) and Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Palhoça, 25 Pedra Branca Avenue, Santa Catarina, Brazil.
Thiago Cesar MartinsExperimental Neuroscience Laboratory (LaNEx) and Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Palhoça, 25 Pedra Branca Avenue, Santa Catarina, Brazil.
Marcio Alvarez-SilvaStem Cell and Bioengineering Laboratory, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, Santa Catarina, Brazil.
Elisa Cristiana Winkelmann-DuarteDepartment of Morphological Sciences, Federal University of Santa Catarina, Santa Catarina, Brazil.
Afonso Shiguemi Inoue SalgadoExperimental Neuroscience Laboratory (LaNEx) and Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Palhoça, 25 Pedra Branca Avenue, Santa Catarina, Brazil.
Francisco José Cidral-FilhoExperimental Neuroscience Laboratory (LaNEx) and Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Palhoça, 25 Pedra Branca Avenue, Santa Catarina, Brazil.
William R ReedDepartment of Physical Therapy, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL USA.
Daniel F MartinsExperimental Neuroscience Laboratory (LaNEx) and Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Palhoça, 25 Pedra Branca Avenue, Santa Catarina, Brazil.
Universidade do Sul de Santa Catarina · BRUniversidade Federal de Santa Catarina · BRUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrovascular accident (CVA) is one of the leading causes of death and disability worldwide, as well as a major financial burden for health care systems. CVA rodent models provide experimental support to determine possible in vivo therapies to reduce brain injury and consequent sequelae. This study analyzed nociceptive, motor, cognitive and mood functions in mice submitted to distal middle cerebral artery (DMCA) occlusion. Male C57BL mice (n = 8) were randomly allocated to control or DMCA groups. Motor function was evaluated with the tests: grip force, rotarod and open field; and nociceptive threshold with von Frey and hot plate assessments. Cognitive function was evaluated with the inhibitory avoidance test, and mood with the tail suspension test. Evaluations were conducted on the seventh- and twenty-eighth-day post DMCA occlusion to assess medium- and long-term effects of the injury, respectively. DMCA occlusion significantly decreases muscle strength and spontaneous locomotion (

Indexed as

Locomotor activityMotor deficitNeuroscienceSensory deficitStroke

Identifiers

PMID32655711
PMCPMC7334328
OpenAlexW3011485731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.