ArticleFrontiers in genetics2020
Integrating Genome-Wide CNVs Into QTLs and High Confidence GWAScore Regions Identified Positional Candidates for Sheep Economic Traits.
Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Whole-Genome Sequencing Reveals Breed-Specific SNPs, Indels, and Signatures of Selection in Royal White and White Dorper Sheep.Animals : an open access journal from MDPI · 2026Article
- Study on the Genomic Basis of Adaptation in Salsk Sheep.Biology · 2025Article
- Genome-wide identification of copy number variation in diverse black pepper accessions.Planta · 2025Article
- Combined Genome-Wide Association Study and Haplotype Analysis Identifies Candidate Genes Affecting Growth Traits of Inner Mongolian Cashmere Goats.Veterinary sciences · 2024Article
- Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheep.Journal of animal science and biotechnology · 2023Article
- The identification of a novel SNP in the resistin (RETN) gene associated with growth traits in Karakul and Awassi sheep.Tropical animal health and production · 2023Article
- High-density SNP markers elucidate the genetic divergence and population structure of Noticiana sheep breed in the Mediterranean context.Frontiers in veterinary science · 2023Article
- Genome-wide analysis of CNVs in three populations of Tibetan sheep using whole-genome resequencing.Frontiers in genetics · 2022Article
- Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems.Genetics, selection, evolution : GSE · 2021Article
- Comparative Signatures of Selection Analyses Identify Loci Under Positive Selection in the Murrah Buffalo of India.Frontiers in genetics · 2021Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Copy number variations (CNVs) are important source of genetic variation, which can affect diverse economic traits through a variety of mechanisms. In addition, genome scan can identify many quantitative trait loci (QTLs) for the economic traits, while genome-wide association studies (GWAS) can localize genetic variants associated with the phenotypic variations. Here, we developed a method called GWAScore which collected GWAS summary data to identify potential candidates, and integrated CNVs into QTLs and high confidence GWAScore regions to detect crucial CNV markers for sheep growth traits. We got 197 candidate genes which were overlapping with the candidate CNVs. Some crucial genes (
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