Evidence map›Paper›PMID 32655518›Full record

ArticleFrontiers in microbiology2020

Inhibition of African Swine Fever Virus Replication by Porcine Type I and Type II Interferons.

Wenhui Fan, Pengtao Jiao, He Zhang, Teng Chen, Xintao Zhou, Yu Qi, Lei Sun, Yingli Shang, Hongfei Zhu, Rongliang Hu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Article
  7. Article
  8. Progress in African Swine Fever Vector Vaccine Development.International journal of molecular sciences · 2025
    Review
  9. Review
  10. InactivatedFrontiers in immunology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Single-cell profiling of African swine fever virus disease in the pig spleen reveals viral and host dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Wenhui FanCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Pengtao JiaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
He ZhangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Teng ChenInstitute of Military Veterinary Medicine, Academy of Military Medical Science, Changchun, China.
Xintao ZhouInstitute of Military Veterinary Medicine, Academy of Military Medical Science, Changchun, China.
Yu QiInstitute of Military Veterinary Medicine, Academy of Military Medical Science, Changchun, China.
Lei SunCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Yingli ShangShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Hongfei ZhuInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Rongliang HuInstitute of Military Veterinary Medicine, Academy of Military Medical Science, Changchun, China.
Wenjun LiuCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Jing LiCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Academy of Military Medical Sciences · CNChinese Academy of Sciences · CNChinese Academy of Agricultural Sciences · CNInstitute of Microbiology · CNShandong Agricultural University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferons (IFNs) are proteins produced by a variety of cells during the process of virus infection. It can activate the transcription of multiple functional genes in cells, regulate the synergistic effect of multiple signaling pathways, and mediate a variety of biological functions such as antiviral activity and immune regulation. The symptoms of hosts infected with African swine fever virus (ASFV) depend on the combined interaction between viruses and the host. However, it is unclear whether IFNs can be used as an emergency preventive treatment for ASFV. This study focused on the use of recombinant porcine IFNs, produced by

Indexed as

African swine fever virusantiviral virus activityMHC moleculesporcine interferonrecombinant

Identifiers

PMID32655518
PMCPMC7325991
OpenAlexW3033188197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.