Evidence map›Paper›PMID 32655483›Full record

ArticleFrontiers in neurology2020

Depletion of ATP Limits Membrane Excitability of Skeletal Muscle by Increasing Both ClC1-Open Probability and Membrane Conductance.

Pieter Arnold Leermakers, Kamilla Løhde Tordrup Dybdahl, Kristian Søborg Husted, Anders Riisager, Frank Vincenzo de Paoli, Tomàs Pinós, John Vissing, Thomas Oliver Brøgger Krag, Thomas Holm Pedersen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Early postoperative hypophosphatemia is an independent predictor of ileus after transforaminal lumbar interbody fusion: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Fatiguing high-intensity intermittent exercise depresses maximal NaPflugers Archiv : European journal of physiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Pieter Arnold LeermakersDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Kamilla Løhde Tordrup DybdahlDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Kristian Søborg HustedDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Anders RiisagerDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Frank Vincenzo de PaoliDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Tomàs PinósMitochondrial and Neuromuscular Disorders Unit, Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain.
John VissingDepartment of Neurology, Rigshospitalet, Copenhagen Neuromuscular Center, University of Copenhagen, Copenhagen, Denmark.
Thomas Oliver Brøgger KragDepartment of Neurology, Rigshospitalet, Copenhagen Neuromuscular Center, University of Copenhagen, Copenhagen, Denmark.
Thomas Holm PedersenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Aarhus University · DKCentre for Biomedical Network Research on Rare Diseases · ESRigshospitalet · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of skeletal muscle contractions require that action potentials can be excited and propagated along the muscle fibers. Recent studies have revealed that muscle fiber excitability is regulated during repeated firing of action potentials by cellular signaling systems that control the function of ion channel that determine the resting membrane conductance (

Indexed as

ATPClC-1fatigueMcArdle diseasemembrane conductancemembrane excitabilityskeletal muscle

Identifiers

PMID32655483
PMCPMC7325937
OpenAlexW3035901709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.