ArticleFrontiers in neuroscience2020
Synchrony Between Default-Mode and Sensorimotor Networks Facilitates Motor Function in Stroke Rehabilitation: A Pilot fMRI Study.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Neural effects of acupuncture on stroke patients with motor dysfunction: an activation likelihood estimation meta-analysis.Frontiers in neurology · 2024Pooled it
- Neuroplastic Mechanisms of Acupuncture in Post-Stroke Motor Recovery: A Randomized Multimodal MRI Trial.CNS neuroscience & therapeutics · 2026Trial
- Enhanced motor recovery in stroke patients through dual-modal intervention: motor imagery and task-oriented robot training.Journal of neuroengineering and rehabilitation · 2025Trial
- Multisensory BCI promotes motor recovery via high-order network-mediated interhemispheric integration in chronic stroke.BMC medicine · 2025Trial
- Investigating acoustic startle priming-induced cortical network reorganization in post-stroke dysarthria: a fNIRS study.Biomedical optics express · 2026Article
- Advancing Stroke Recovery Through Operant Conditioning of Corticomuscular Coherence.Restorative neurology and neuroscience · 2026Review
- Impairment of brain short association fibers across clinical stages in amyotrophic lateral sclerosis: a new biomarker mirroring disease progression.BMC medicine · 2026Article
- Genetic evidence for causal relationships between brain functional networks and domain-specific recovery after nondisabling ischemic stroke.Experimental biology and medicine (Maywood, N.J.) · 2026Article
- Temporal dynamics of offline transcranial ultrasound stimulation.Current research in neurobiology · 2025Article
- Thalamic oscillatory dysrhythmia and disrupted functional connectivity in thalamocortical loops in perinatal stroke.Scientific reports · 2025Article
- Alterations of static and dynamic changes in intrinsic brain activity and its relation to behavioral outcomes in subcortical ischemic stroke after one-month intervention.Scientific reports · 2025Article
- Article
- Disconnection syndromes and injury to neural systems after ischemic stroke.Frontiers in stroke · 2025Article
- Differences in motor network reorganization between patients with good and poor upper extremity impairment outcomes after stroke.Brain imaging and behavior · 2024Article
- Motor performance and functional connectivity between the posterior cingulate cortex and supplementary motor cortex in bipolar and unipolar depression.European archives of psychiatry and clinical neuroscience · 2024Article
- Resting-state functional magnetic resonance imaging indices are related to electrophysiological dysfunction in degenerative cervical myelopathy.Scientific reports · 2024Article
- Cortical structural network characteristics in non-cognitive impairment end-stage renal disease.Frontiers in neuroscience · 2024Article
- Reorganization of Dynamic Network in Stroke Patients and Its Potential for Predicting Motor Recovery.Neural plasticity · 2024Article
- Connectomics underlying motor functional outcomes in the acute period following stroke.Frontiers in aging neuroscience · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stroke is the most common cause of complex disability in Taiwan. After stroke onset, persistent physical practice or exercise in the rehabilitation procedure reorganizes neural assembly for reducing motor deficits, known as neuroplasticity. Neuroimaging literature showed rehabilitative effects specific to the brain networks of the sensorimotor network (SMN) and default-mode network (DMN). However, whether between-network interactions facilitate the neuroplasticity after stroke rehabilitation remains a mystery. Therefore, we conducted the longitudinal assessment protocol of stroke rehabilitation, including three types of clinical evaluations and two types of functional magnetic resonance imaging (fMRI) techniques (resting state and grasp task). Twelve chronic stroke patients completed the rehabilitation protocol for at least 24 h and finished the three-time assessments: before, after rehabilitation, and 1 month after the cessation of rehabilitation. For comparison, age-matched normal controls (NC) underwent the same fMRI evaluation once without repeated measure. Increasing scores of the Fugl-Meyer assessment (FMA) and upper extremity performance test reflected the enhanced motor performances after the stroke rehabilitation process. Analysis of covariance (ANCOVA) results showed that the connections between posterior cingulate cortex (PCC) and iM1 were persistently enhanced in contrast to the pre-rehabilitation condition. The interactions between PCC and SMN were positively associated with motor performances. The enhanced cross-network connectivity facilitates the motor recovery after stroke rehabilitation, but the cross-network interaction was low before the rehabilitation process, similar to the level of NCs. Our findings suggested that cross-network connectivity plays a facilitatory role following the stroke rehabilitation, which can serve as a neurorehabilitative biomarker for future intervention evaluations.
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