Evidence map›Paper›PMID 32655295›Full record

ArticleCurrent genomics2020

Extremely-randomized-tree-based Prediction of N

Rajiv G Govindaraj, Sathiyamoorthy Subramaniyam, Balachandran Manavalan

Abstract read
In one paragraph

Article in Current genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Deep-4mCGP: A Deep Learning Approach to Predict 4mC Sites inInternational journal of molecular sciences · 2022
    Article
  5. Article
  6. Article
  7. Identification ofComputational and mathematical methods in medicine · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Fast and Accurate Classification of Meta-Genomics Long Reads With deSAMBA.Frontiers in cell and developmental biology · 2021
    Article
  12. Review
  13. Computational RNA Epigenetics.Current genomics · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rajiv G Govindaraj1HotSpot Therapeutics, 50 Milk Street, 16 Floor, Boston, MA02109, USA; 2Research and Development Center, In-silicogen Inc., Yongin-si 16954, Gyeonggi-do, Republic of Korea; 3Department of Biotechnology, Dr. N.G.P. Arts and Science College, Coimbatore, Tamil Nadu641048, India; 4Department of Physiology, Ajou University School of Medicine, Suwon, Republic of Korea.
Sathiyamoorthy Subramaniyam1HotSpot Therapeutics, 50 Milk Street, 16 Floor, Boston, MA02109, USA; 2Research and Development Center, In-silicogen Inc., Yongin-si 16954, Gyeonggi-do, Republic of Korea; 3Department of Biotechnology, Dr. N.G.P. Arts and Science College, Coimbatore, Tamil Nadu641048, India; 4Department of Physiology, Ajou University School of Medicine, Suwon, Republic of Korea.
Balachandran Manavalan1HotSpot Therapeutics, 50 Milk Street, 16 Floor, Boston, MA02109, USA; 2Research and Development Center, In-silicogen Inc., Yongin-si 16954, Gyeonggi-do, Republic of Korea; 3Department of Biotechnology, Dr. N.G.P. Arts and Science College, Coimbatore, Tamil Nadu641048, India; 4Department of Physiology, Ajou University School of Medicine, Suwon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionN METHODOLOGY: In this study, we proposed a novel computational predictor termed ERT-m6Apred, for the accurate prediction of m6A sites. To identify the feature encodings with more discriminative capability, we applied a two-step feature selection technique on seven different feature encodings and identified the corresponding optimal feature set.

resultsSubsequently, performance comparison of the corresponding optimal feature set-based extremely randomized tree model revealed that Pseudo k-tuple composition encoding, which includes 14 physicochemical properties significantly outperformed other encodings. Moreover, ERT-m6Apred achieved an accuracy of 78.84% during cross-validation analysis, which is comparatively better than recently reported predictors.

conclusionIn summary, ERT-m6Apred predicts

Indexed as

cross-validationExtremely randomized treefeature optimizationN6-methyladenosine sitesRNA sequencesSaccharomyces cerevisiae

Identifiers

PMID32655295
PMCPMC7324895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.