SynthesisWorld journal of gastroenterology2020
Clinical efficacy of the over-the-scope clip device: A systematic review.
Synthesis in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Efficacy of endoscopic over-the-scope clip fixation for preventing migration of self-expandable metal stents: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- Stent Management of Leaks After Bariatric Surgery: a Systematic Review and Meta-analysis.Obesity surgery · 2022Pooled it
- Barbed suture-assisted tension reduction and de-epithelialization for clip closure of a fecalith-associated rectal fistula.Endoscopy · 2026Article
- Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Post-Bariatric Surgery Complications and the Role of Endoscopic Intervention.Diagnostics (Basel, Switzerland) · 2026Review
- A pilot study on the application and efficacy of mucosal traction-assisted clip closure in endoscopic full-thickness resection for gastric submucosal tumors.Scientific reports · 2026Article
- Successful Endoscopic Removal and Closure of a Large Esophageal Perforation Following Accidental Ingestion of a Dental Prosthesis.DEN open · 2026Article
- Interventional Endoscopy for the Management of Post-Surgical Leaks and Fistulas: A Scoping Review.Journal of clinical medicine · 2026Review
- Endoscopic clip systems for hemostasis and defect closure in gastrointestinal endoscopy.World journal of gastrointestinal endoscopy · 2026Review
- Expanded options for removal of an old over-the-scope clip.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Over-the-Scope Endoscopic Clip as Rescue Therapy for Massive Esophageal Variceal Bleeding.Gastro hep advances · 2026Article
- A novel enhanced two-tooth clip for reliable defect closure endoscopically: An ex vivo comparative and in vivo feasibility study.Surgical endoscopy · 2026Article
- Congenital aerodigestive fistula with extraordinarily delayed adult presentation: a case report and review of endoscopic closure for bronchoesophageal fistula.Frontiers in medicine · 2026Article
- Severe Recurrent Gastrointestinal Bleeding and Diagnostic Dilemmas in Zollinger-Ellison Syndrome: A Case Report.GE Portuguese journal of gastroenterology · 2025Article
- Over-the-scope clip on over-the-scope clip technique for closure of delayed perforation near a previously placed over-the-scope clip.Endoscopy · 2025Article
- Endoscopic Closure Techniques for Perforations, Leaks, and Fistulae: Review Article.GE Portuguese journal of gastroenterology · 2025Review
- Advancements in endoscopic closure: Embracing a new era of managing complications and postprocedural defects after endoscopic submucosal dissection.World journal of gastrointestinal endoscopy · 2025Review
- Advances in endoscopic closure techniques for endoscopic full-thickness resection.World journal of gastrointestinal endoscopy · 2025Review
- Closing the gap: endoscopic treatment of esophageal anastomotic leakage-a retrospective cohort study.Surgical endoscopy · 2025Article
- Detachable over-the-scope clip for colon defects in the trans intestinal natural orifice transluminal endoscopic cholecystolithotomy: A case report.World journal of gastrointestinal endoscopy · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe over-the-scope clip (OTSC) system has been increasingly utilized as a non-surgical option to endoscopically manage refractory gastrointestinal (GI) hemorrhage, perforations/luminal defects and fistulas. Limited data exist evaluating the efficacy and safety of OTSC.
aimTo determine the clinical success and adverse event (AE) rates of OTSC across all GI indications.
methodsA PubMed search was conducted for eligible articles describing the application of the OTSC system for any indication in the GI tract. Any article or case series reporting data for less than 5 total patients was excluded. The primary outcome was the rate of clinical success. Secondary outcomes included: Technical success rate, OTSC-related AE rate and requirement for surgical intervention despite-OTSC placement. Pooled rates (per-indication and overall) were calculated as the number of patients with the event of interest divided by the total number of patients.
resultsA total of 85 articles met our inclusion criteria (
conclusionThis systematic review demonstrates that the OTSC system is a safe and effective endoscopic therapy to manage GI hemorrhage, perforations, anastomotic leaks, defects created by endoscopic resections and for stent fixation. Clinical success in fistula management appears limited. Further studies, including randomized controlled trials comparing OTSC with conventional and/or surgical therapies, are needed to determine which indication(s) are the most effective for its use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.