Evidence map›Paper›PMID 32655187›Full record

ArticleJournal of molecular structure2020

Synthesis, biological evaluation, and modeling studies of 1,3-disubstituted cyclobutane-containing analogs of combretastatin A4.

Andrii Malashchuk, Anton V Chernykh, Vasyl V Hurmach, Maxim O Platonov, Oleksandra Onopchenko, Sergey Zozulya, Constantin G Daniliuc, Alexey V Dobrydnev, Ivan S Kondratov, Yuriy S Moroz and 1 more

Abstract read
In one paragraph

Article in Journal of molecular structure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrii MalashchukEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Anton V ChernykhEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Vasyl V HurmachEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Maxim O PlatonovEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Oleksandra OnopchenkoBienta/Enamine Ltd. (www.bienta.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Sergey ZozulyaBienta/Enamine Ltd. (www.bienta.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Constantin G DaniliucOrganisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
Alexey V DobrydnevEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Ivan S KondratovEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.
Yuriy S MorozTaras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine.
Oleksandr O GrygorenkoEnamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.

Funding

Ultra-large library docking for ligand discoveryR01GM133836 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI IRWIN, JOHN J. · 2019 to 2022
$1.6M
NIGMS NIH HHS R01 GM133836
6 · The paper itself

Abstract

With the aim of circumventing the adverse

Indexed as

CombretastatinConformational restrictionCyclobutaneMolecular dynamicsTubulin

Identifiers

PMID32655187
PMCPMC7351177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.