ArticleMedical science monitor : international medical journal of experimental and clinical research2020
Structure Design and Optimization of the C5-C6 Cervical Intervertebral Fusion Cage Using the Anterior Cervical Plate and Cage Fixation System.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The fifth and sixth cervical vertebra (C5-C6) is the most easily injured segment encountered in clinical practice. The anterior cervical plate and cage (ACPC) fixation system is always used to reconstruct the intervertebral height and maintain the segmental stability. The postoperative effect, such as subsidence, neck pain, and non-fusion, is greatly affected by the cervical cage structure design. This study determined reasonable structure size parameters that present optimized biomechanical properties related to the postoperative subsidence often accompanied with ACPC. MATERIAL AND METHODS Twenty bionic cages with different structural sizes (distance between the center of the cage and groove, groove depth, and groove width) were designed and analyzed based on the regression optimization design and analysis method combined with FE analysis. Because a previous study showed that greater stresses on the endplate are associated with higher risk of subsidence, the optimization object was selected as the stresses on endplate to lower it. RESULTS The postoperative stresses on the endplate of all cages with bionic structure design were proved to be lower than with the original one. The optimal structure size was the distance between the center of the cage and groove=0 mm, groove depth=3 mm, and groove width=4 mm. Regression analysis found the cage with optimized bionic structural parameters resulted in a 22.58% reduction of endplate stress response compared with the original one. CONCLUSIONS The bionic cage with optimized structural sizes can reduce the subsidence risk, suggesting that the optimization method has great potential applications in the biomechanical engineering field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.