Evidence map›Paper›PMID 32655015›Full record

ArticleMolecules and cells2020

Enhancer Function of MicroRNA-3681 Derived from Long Terminal Repeats Represses the Activity of Variable Number Tandem Repeats in the 3' UTR of

Hee-Eun Lee, Sang-Je Park, Jae-Won Huh, Hiroo Imai, Heui-Soo Kim

Open access · greenAbstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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  7. Identification and Analysis ofFrontiers in aging neuroscience · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hee-Eun LeeDepartment of Integrated Biological Science, Pusan National University, Busan 46241, Korea.ORCID https://orcid.org/0000-0002-7485-9083
Sang-Je ParkNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Korea.ORCID https://orcid.org/0000-0002-3371-9092
Jae-Won HuhNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Korea.ORCID https://orcid.org/0000-0001-5845-939X
Hiroo ImaiDepartment of Cellular and Molecular Biology, Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.ORCID https://orcid.org/0000-0003-0729-0322
Heui-Soo KimInstitute of Systems Biology, Pusan National University, Busan 46241, Korea.ORCID https://orcid.org/0000-0002-5226-6594
Korea Research Institute of Bioscience and Biotechnology · KRKyoto University · JPPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

microRNAs (miRNAs) are non-coding RNA molecules involved in the regulation of gene expression. miRNAs inhibit gene expression by binding to the 3' untranslated region (UTR) of their target gene. miRNAs can originate from transposable elements (TEs), which comprise approximately half of the eukaryotic genome and one type of TE, called the long terminal repeat (LTR) is found in class of retrotransposons. Amongst the miRNAs derived from LTR, hsa-miR-3681 was chosen and analyzed using bioinformatics tools and experimental analysis. Studies on hsa-miR-3681 have been scarce and this study provides the relative expression analysis of hsa-miR-3681-5p from humans, chimpanzees, crab-eating monkeys, and mice. Luciferase assay for hsa-miR-3681-5p and its target gene

Indexed as

Enhancer Elements, Genetic3' Untranslated RegionsAmino Acid SequenceAnimalsBinding SitesCell Line, TumorComputational BiologyFemaleGene Expression RegulationHaplorhiniHumansMaleMembrane ProteinsMiceMicroRNAsMinisatellite Repeats3' Untranslated RegionsMembrane ProteinsMicroRNAsNerve Tissue ProteinsRNA Recognition Motif ProteinsShisa7 protein, mouseHISA7long terminal repeatmiR-3681-5ptransposable elementsvariable number tandem repeat

Identifiers

PMID32655015
PMCPMC7398795
OpenAlexW3043385622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.