Evidence map›Paper›PMID 32654891›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2020

Arteriovenous Fistula Placement, Maturation, and Patency Loss in Older Patients Initiating Hemodialysis.

Joyce Z Qian, Mara McAdams-DeMarco, Derek K Ng, Bryan Lau

Open access · greenAbstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
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  9. Article
  10. Is the Fistula First Approach still valid?Jornal brasileiro de nefrologia
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joyce Z QianMedical Technology and Practice Patterns Institute, Bethesda, MD; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD. Electronic address: joyce@mtppi.org.
Mara McAdams-DeMarcoDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD; Department of Surgery, School of Medicine, Johns Hopkins University, Baltimore, MD.
Derek K NgDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Bryan LauDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Kidney transplantation in older, frail and cognitively impaired adults with ESRD: Balancing utility vs. justiceR01AG055781 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2017 to 2021
$4.2M
Hemodialysis-based interventions to preserve cognitive functionR01DK114074 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2018 to 2022
$3.9M
Developing personalized immunosuppression for older kidney transplant recipientsR01DK120518 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2019 to 2022
$2.7M
Barriers to arteriovenous fistula use in black hemodialysis patientsR01MD013818 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLON, MICHAEL · 2019 to 2023
$2.3M
Choice of vascular access and patient outcomes among older hemodialysis patientsR21DK104248 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLON, MICHAEL · 2015 to 2016
$432k
Impact of Recent Payment Reform on Dialysis Modality Choice among ESRD PatientsR03HS022931 · AHRQ · MEDICAL TECHNOLOGY AND PRACTICE PATTERNS · PI ZHANG, YI · 2014 to 2015
$99k
AHRQ HHS R03 HS022931NIA NIH HHS R01 AG055781NIDDK NIH HHS R01 DK114074NIDDK NIH HHS R01 DK120518NIDDK NIH HHS R21 DK104248NIMHD NIH HHS R01 MD013818
6 · The paper itself

Abstract

RATIONALE &

objectiveThe current clinical guidelines for vascular access do not have specific recommendations for older hemodialysis patients. Our study aimed to determine the association of age with arteriovenous fistula (AVF) placement, maturation, and primary and secondary patency loss among older hemodialysis recipients. STUDY

designRetrospective cohort study. SETTING &

participantsA US national cohort of incident hemodialysis patients 67 years or older (N = 43,851) assembled from the US Renal Data System. EXPOSURE: Age at dialysis initiation. OUTCOMES: AVF placement, maturation, primary patency loss, and abandonment. ANALYTICAL APPROACH: Cause-specific and subdistribution proportional hazards models were used to examine the association of age and AVF outcomes, with kidney transplantation, peritoneal dialysis, and death treated as competing events. Age cutoff was identified by restricted cubic splines. We compared crude and inverse probability-weighted cumulative incidence functions using Gray's test.

resultsAs compared with those aged 67-<77 years, patients 77 years or older had significantly lower probabilities of AVF placement (adjusted cause-specific HR [cHR], 0.96 [95% CI, 0.92-0.99]; adjusted subdistribution HR [sHR], 0.92 [95% CI, 0.89-0.95]; Gray's test P < 0.001) and maturation (adjusted cHR, 0.95 [95% CI, 0.91-0.99]; adjusted sHR, 0.93 [95% CI, 0.90-0.97]; P < 0.001). However, age was not associated with AVF primary (adjusted cHR, 1.05 [95% CI, 1.00-1.11]; adjusted sHR, 1.04 [95% CI, 0.99-1.09]; P = 0.09) or secondary (adjusted cHR, 1.06 [95% CI, 0.94-1.20]; adjusted sHR, 1.05 [95% CI, 0.93-1.18]; P = 0.4) patency loss. LIMITATIONS: Reliance on administrative claims to ascertain AVF outcomes.

conclusionsThe likelihood of AVF maturation is an important consideration for vascular access planning. Age alone should not be the basis for excluding older dialysis patients from AVF creation because maintenance of fistula patency was not reduced with older age despite a modest reduction in fistula maturation.

Indexed as

Arteriovenous Shunt, SurgicalRenal DialysisAgedCohort StudiesFemaleHumansMaleRetrospective StudiesVascular Patencyagearteriovenous fistula (AVF)AVF outcomecompeting riskselderlyend-stage renal disease (ESRD)Hemodialysisindividualized treatment planmaturationolder adultspatencyplacementsurvival analysisvascular access

Identifiers

PMID32654891
PMCPMC7534584
OpenAlexW3041899883

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.