Additional Trials of Vitamin C in Septic Shock: A Bag of Mixed Fruit.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

1. Vitamin C deficiency in critically ill COVID-19 patients admitted to intensive care unit.Frontiers in medicine · 2023
   Article
2. Measuring vitamin C in critically ill patients: clinical importance and practical difficulties-Is it time for a surrogate marker?Critical care (London, England) · 2021
   Review
3. Early high-dose vitamin C in post-cardiac arrest syndrome (VITaCCA): study protocol for a randomized, double-blind, multi-center, placebo-controlled trial.Trials · 2021
   Article
4. Rapid screening of critically ill patients for low plasma vitamin C concentrations using a point-of-care oxidation-reduction potential measurement.Intensive care medicine experimental · 2021
   Article
5. Vitamin C and thiamine for sepsis: time to go back to fundamental principles.Intensive care medicine · 2020
   Article
6. Comparison of the effects of vitamin C and thiamine on refractory hypotension in patients with sepsis: A randomized controlled trial.International journal of critical illness and injury science
   Article

Corrections and comments

• Commented on by
  Would You Withhold Fruit From the Critically Ill?2021
• Comment on
  Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis: The ORANGES Trial.2020
• Comment on
  Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock: A Randomized Controlled Trial.2020

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as