ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
The impact of global selection on local adaptation and reproductive isolation.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Genomic analyses inEvolution letters · 2026Article
- Ecotypic divergence in Mongolian Scots pine persists via large-effect genetic adaptation and phenotypic plasticity.BMC plant biology · 2025Article
- Demographically explicit scans for barriers to gene flow using gIMble.PLoS genetics · 2023Article
- Does selection occur at the intermediate zone of two insufficiently isolated populations? A whole-genome analysis along an altitudinal gradient.Journal of plant research · 2023Article
- Adaptive, maladaptive, neutral, or absent plasticity: Hidden caveats of reaction norms.Evolutionary applications · 2023Article
- The rates of introgression and barriers to genetic exchange between hybridizing species: sex chromosomes vs autosomes.Genetics · 2021Article
- Towards the completion of speciation: the evolution of reproductive isolation beyond the first barriers.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- On the completion of speciation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the homogenizing effect of strong gene flow between two populations, adaptation under symmetric divergent selection pressures results in partial reproductive isolation: adaptive substitutions act as local barriers to gene flow, and if divergent selection continues unimpeded, this will result in complete reproductive isolation of the two populations, i.e. speciation. However, a key issue in framing the process of speciation as a tension between local adaptation and the homogenizing force of gene flow is that the mutation process is blind to changes in the environment and therefore tends to limit adaptation. Here we investigate how globally beneficial mutations (GBMs) affect divergent local adaptation and reproductive isolation. When phenotypic divergence is finite, we show that the presence of GBMs limits local adaptation, generating a persistent genetic load at the loci that contribute to the trait under divergent selection and reducing genome-wide divergence. Furthermore, we show that while GBMs cannot prohibit the process of continuous differentiation, they induce a substantial delay in the genome-wide shutdown of gene flow. This article is part of the theme issue 'Towards the completion of speciation: the evolution of reproductive isolation beyond the first barriers'.
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