ArticlePlant biotechnology journal2021
High-resolution temporal dynamic transcriptome landscape reveals a GhCAL-mediated flowering regulatory pathway in cotton (Gossypium hirsutum L.).
Article in Plant biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- GmMADS17, a MADS-box transcription factor, promotes flowering in soybean.BMC plant biology · 2026Article
- Branch architecture and flowering time are separately regulated by GhFL and GhSP2 in cotton.The Plant journal : for cell and molecular biology · 2026Article
- Integrated phylogenomic and transcriptomic analyses reveal GhTZP3 as a key gene regulating flowering time and undergoing artificial selection in upland cotton (Gossypium hirsutum).Functional & integrative genomics · 2026Article
- MiABI5-like7-Horticulture research · 2026Article
- Speed breeding in upland cotton (Frontiers in plant science · 2026Review
- Genome-Wide Identification ofPlants (Basel, Switzerland) · 2025Article
- Understanding the role of GhRCC1.61 in flowering time in upland cotton through integrated analyses of gene family, RNA-seq, VIGS and allelic variation.Plant cell reports · 2025Article
- Genome-wide identification of boron transporters (GhBORs) in upland cotton and the role of GhBOR1 in promoting flowering.BMC plant biology · 2025Article
- Genome-wide association study reveals novel SNP loci and candidate genes linked to flowering time in upland cotton.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Spatiotemporal dynamics of benzylisoquinoline alkaloid gene expression and co-expression networks during Papaver Somniferum developmental stages.Scientific reports · 2025Article
- Exploring Metabolic Pathways and Gene Mining During Cotton Flower Bud Differentiation Stages Based on Transcriptomics and Metabolomics.International journal of molecular sciences · 2025Article
- Comparative Analysis of Floral Transcriptomes inPlants (Basel, Switzerland) · 2025Article
- From juvenile to adult: investigating miRNAs, gene expression, and the juvenile cone in olive development.Frontiers in plant science · 2025Article
- Identification of QTLs for early maturity-related traits based on RIL population of two elite cotton cultivars.BMC plant biology · 2024Article
- A Novel Gene,International journal of molecular sciences · 2024Article
- Integrating RTM-GWAS and meta‑QTL data revealed genomic regions and candidate genes associated with the first fruit branch node and its height in upland cotton.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- GhGASA14 regulates the flowering time of upland cotton in response to GAPlant cell reports · 2024Article
- The 4Fs of cotton: genome editing of cotton for fiber, food, feed, and fuel to achieve zero hunger.Frontiers in genome editing · 2024Review
- Functional dissection of phytochrome A in plants.Frontiers in plant science · 2024Review
- A comprehensive overview of cotton genomics, biotechnology and molecular biological studies.Science China. Life sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transition from vegetative to reproductive growth is very important for early maturity in cotton. However, the genetic control of this highly dynamic and complex developmental process remains unclear. A high-resolution tissue- and stage-specific transcriptome profile was generated from six developmental stages using 72 samples of two early-maturing and two late-maturing cotton varieties. The results of histological analysis of paraffin sections showed that flower bud differentiation occurred at the third true leaf stage (3TLS) in early-maturing varieties, but at the fifth true leaf stage (5TLS) in late-maturing varieties. Using pairwise comparison and weighted gene co-expression network analysis, 5312 differentially expressed genes were obtained, which were divided into 10 gene co-expression modules. In the MElightcyan module, 46 candidate genes regulating cotton flower bud differentiation were identified and expressed at the flower bud differentiation stage. A novel key regulatory gene related to flower bud differentiation, GhCAL, was identified in the MElightcyan module. Anti-GhCAL transgenic cotton plants exhibited late flower bud differentiation and flowering time. GhCAL formed heterodimers with GhAP1-A04/GhAGL6-D09 and regulated the expression of GhAP1-A04 and GhAGL6-D09. GhAP1-A04- and GhAGL6-D09-silenced plants also showed significant late flowering. Finally, we propose a new flowering regulatory pathway mediated by GhCAL. This study elucidated the molecular mechanism of cotton flowering regulation and provides good genetic resources for cotton early-maturing breeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.