ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021
Effects of body mass index on kidney transplant outcomes are significantly modified by patient characteristics.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Guideline
- Impact of obesity and income on the likelihood of kidney transplantation: A retrospective cohort study.World journal of transplantation · 2026Article
- Elevated leucine-rich alpha-2 glycoprotein levels and mortality risk in end-stage renal disease: evidence for gender differences.Clinical kidney journal · 2026Article
- The obese transplant organ recipient: experimental and clinical evidence for tailored immunosuppression.Transplant international : official journal of the European Society for Organ Transplantation · 2026Review
- Association of Myosteatosis and of Graft Loss after Kidney Transplantation: An International Observational Study.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Should Kidney Transplantation be Offered to Patients with Body Mass Index >40?: Commentary.Kidney360 · 2025Article
- Higher daily protein intake was a protective factor for graft function of kidney transplant recipients in the early post-transplant period: a retrospective cohort study.BMC nephrology · 2025Observational
- Evaluating Hyperparathyroidism in Simultaneous Pancreas-Kidney Transplant Recipients: A Single-Center Experience.Clinical transplantation · 2025Article
- Obesity-associated Inflammation and Alloimmunity.Transplantation · 2025Review
- Comparative analysis of outcomes in high KDPI spectrum kidney transplants using unsupervised machine learning algorithm.PloS one · 2025Article
- Body mass index in pediatric kidney transplant selection criteria.Pediatric nephrology (Berlin, Germany) · 2024Article
- Successful Surgical Management of Grade 4 Gynecomastia in a Renal Transplant Recipient.Plastic and reconstructive surgery. Global open · 2024Article
- Assessing Patients beyond the Simple Optics of BMI: The Concomitant Role of Sarcopenia and BMI in Predicting Kidney Transplant Outcomes.Life (Basel, Switzerland) · 2024Article
- Exploration of wound-related complications post-kidney transplantation.International wound journal · 2024Observational
- The Impact and Effectiveness of Weight Loss on Kidney Transplant Outcomes: A Narrative Review.Nutrients · 2023Review
- Post-kidney transplant body mass index trajectories are associated with graft loss and mortality.Clinical transplantation · 2023Article
- Body mass index affects kidney transplant outcomes: A cohort study over 5 years using a steroid sparing protocol.Frontiers in endocrinology · 2023Observational
- First Testing of Literature-Based Models for Predicting Increase in Body Weight and Adipose Tissue Mass After Kidney Transplantation.Progress in transplantation (Aliso Viejo, Calif.) · 2022Article
- Bariatric Surgery Decreases Barriers for Kidney Transplant: Are There Other Weight-Loss Options?Kidney360 · 2022Article
- Machine Learning Consensus Clustering of Morbidly Obese Kidney Transplant Recipients in the United States.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Body mass index (BMI) is a known risk factor associated with kidney transplant outcomes and is incorporated for determining transplant candidate eligibility. However, BMI is a coarse health measure and risks associated with BMI may vary by patient characteristics. We evaluated 296 807 adult (age > 17) solitary kidney transplant recipients from the Scientific Registry of Transplant Recipients (2000-2019). We examined effects of BMI using survival models and tested interactions with recipient characteristics. Overall, BMI demonstrated a "J-Shaped" risk profile with elevated risks for overall graft loss with low BMI and obesity. However, multivariable models indicated interactions between BMI with recipient age, diagnosis, gender, and race/ethnicity. Low BMI was relatively higher risk for older recipients (>60 years), people with type I diabetes, and males and demonstrated no additional risk among younger (18-39) and Hispanic recipients. High BMI was associated with elevated risk for Caucasians and attenuated risk among African Americans and people with type II diabetes. Effects of BMI had variable risks for mortality vs graft loss by recipient characteristics in competing risks models. The association of BMI with posttransplant outcomes is highly variable among kidney transplant recipients. Results are important considerations for personalized care and risk stratification. Findings suggest that transplant contraindications should not be based on absolute BMI thresholds but modified based on patient characteristics.
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