ArticleBrain pathology (Zurich, Switzerland)2021
Neonatal apneic phenotype in a murine congenital central hypoventilation syndrome model is induced through non-cell autonomous developmental mechanisms.
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Article in Brain pathology (Zurich, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits.Brain, behavior, and immunity · 2024Article
- DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.Alzheimer's research & therapy · 2024Article
- Multigenerational inheritance of breathing deficits following perinatal exposure to titanium dioxide nanoparticles in the offspring of mice.Discover nano · 2024Article
- Article
- Machine learning approaches reveal subtle differences in breathing and sleep fragmentation inJournal of neurophysiology · 2021Article
- Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation.Frontiers in immunology · 2021Article
- Machine learning-based data analytic approaches for evaluating post-natal mouse respiratory physiological evolution.Respiratory physiology & neurobiology · 2021Article
- Research Advances on Therapeutic Approaches to Congenital Central Hypoventilation Syndrome (CCHS).Frontiers in neuroscience · 2020Review
- Revisiting the Neuropathology of Sudden Infant Death Syndrome (SIDS).Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
25 authors at 5 institutions in 3 countries.
Diego Alzate-CorreaDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Jillian Mei-Ling LiuDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Mikayla JonesDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Talita M SilvaDepartment of Physiology and Biophysics, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil.
Michele Joana AlvesDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Elizabeth BurkeDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Jessica ZuñigaDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Behiye KayaDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Giuliana ZazaDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Mehmet Tahir AslanDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Jessica BlackburnDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Marina Y ShimadaDepartment of Physiology and Biophysics, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil.
Silvio A Fernandes-JuniorDepartment of Pharmacology, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil.
Lisa A BaerDepartment of Physiology and Cell Biology, The Ohio State University College of Medicine, Columbus, OH, USA.
Kristin I StanfordDepartment of Physiology and Cell Biology, The Ohio State University College of Medicine, Columbus, OH, USA.
Amber KemptonDepartment of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
Sakima SmithDepartment of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
Caroline C SzujewskiInstitute for Integrative Physiology, Grossman Institute for Neuroscience Quantitative Biology and Human Behavior, The Committee on Neurobiology, The University of Chicago, Chicago, IL, USA.
Abby SilbaughInstitute for Integrative Physiology, Grossman Institute for Neuroscience Quantitative Biology and Human Behavior, The Committee on Neurobiology, The University of Chicago, Chicago, IL, USA.
Jean-Charles ViemariP3M Team, Institut de Neurosciences de la Timone, UMR 7289 AMU-CNRS, Marseille, France.
Ana C TakakuraDepartment of Pharmacology, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil.ORCID 0000-0001-6273-0760
Alfredo J GarciaInstitute for Integrative Physiology, Grossman Institute for Neuroscience Quantitative Biology and Human Behavior, The Committee on Neurobiology, The University of Chicago, Chicago, IL, USA.
Thiago S MoreiraDepartment of Physiology and Biophysics, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil.
Catherine M CzeislerDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
José J OteroDivision of Neuropathology, Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.ORCID 0000-0003-0680-4520
The Ohio State University · USUniversidade de São Paulo · BRChicago Institute for Psychoanalysis · USZero to Three · USCentre National de la Recherche Scientifique · FR
Funding
Integrative Consequences of HypoxiaP01HL090554 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2008 to 2017
$21.4MMechanisms Underlying Sympathetic Activation-dependent Endothelial Cell Activation by Chronic Intermittent HypoxiaP01HL144454 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2019 to 2023
$12.7MIntegrative Training in the Neurobiology of Addictive BehaviorsT32DA043469 · NIDA · UNIVERSITY OF CHICAGO · PI Donald Hedeker, Xiaoxi Zhuang · 2017 to 2026
$3.8MMechanisms of Congenital HypoventilationR01HL132355 · NHLBI · OHIO STATE UNIVERSITY · PI CZEISLER, CATHERINE, OTERO, JOSE JAVIER · 2016 to 2020
$2.5MA Novel Role for Brown Adipose Tissue Enhance Heart Function and MetabolismR01HL138738 · NHLBI · OHIO STATE UNIVERSITY · PI STANFORD, KRISTIN I · 2017 to 2021
$2.3MNeurocognitive Consequences of Intermittent HypoxiaR01NS107421 · NINDS · UNIVERSITY OF CHICAGO · PI GARCIA, ALFREDO J · 2018 to 2022
$2.3MDefining New Pathways in Heart Failure and ArrhythmiaK08HL135437 · NHLBI · OHIO STATE UNIVERSITY · PI SMITH, SAKIMA AHMAD · 2017 to 2021
$749kAmerican Heart Association 17CSA33610078NHLBI NIH HHS K08 HL135437NHLBI NIH HHS P01 HL090554NHLBI NIH HHS P01 HL144454NHLBI NIH HHS R01 HL132355NHLBI NIH HHS R01 HL138738NIDA NIH HHS T32 DA043469NINDS NIH HHS R01 NS107421NINDS NIH HHS R01 NS10742101Universidade de São Paulo 2015/23376Universidade de São Paulo 2015/23376-1Universidade de São Paulo 2016/23281-3Universidade de São Paulo 2017/12678-2
Abstract
Congenital central hypoventilation syndrome (CCHS) represents a rare genetic disorder usually caused by mutations in the homeodomain transcription factor PHOX2B. Some CCHS patients suffer mainly from deficiencies in CO
Indexed as
AnimalsAnimals, NewbornApneaDisease Models, AnimalHomeodomain ProteinsHypoventilationMiceMotor NeuronsNeurogenesisPhenotypeSleep Apnea, CentralTranscription FactorsHomeodomain ProteinsPhox2b protein, mouseTranscription Factorsapneachemosensationcongenital central hypoventilation syndrome (CCHS)Nkx2.2PHOX2Brespiratory rhythm-generating networks
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.