Evidence map›Paper›PMID 32654244›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2021

Discordant courses of COVID-19 in a cohabiting couple of lung transplant recipients.

Nadine Desmazes-Dufeu, Bérengère Coltey, Lyria Amari, Marion Gouitaa, Camille Touzery, Martine Reynaud-Gaubert, Pascal Chanez, Nadim Cassir

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Management of lung transplantation in the COVID-19 era-An international survey.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  6. Discordant courses of COVID-19 in a cohabiting couple of lung transplant recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nadine Desmazes-DufeuService de Pneumologie, Équipe de Transplantation Pulmonaire, Hôpital Nord, Assistance Publique Hôpitaux de Marseille (APHM), Marseille, France.
Bérengère ColteyService de Pneumologie, Équipe de Transplantation Pulmonaire, Hôpital Nord, Assistance Publique Hôpitaux de Marseille (APHM), Marseille, France.
Lyria AmariService de Pneumologie, Équipe de Transplantation Pulmonaire, Hôpital Nord, Assistance Publique Hôpitaux de Marseille (APHM), Marseille, France.
Marion GouitaaClinique des Bronches, Allergie et Sommeil/APHM, Marseille C2VN Center INSERM INRAE UMR1062, Aix-Marseille Université, Marseille, France.
Camille TouzeryService de Radiologie, Hôpital Nord, APHM, Marseille, France.
Martine Reynaud-GaubertService de Pneumologie, Équipe de Transplantation Pulmonaire, Hôpital Nord, Assistance Publique Hôpitaux de Marseille (APHM), Marseille, France.
Pascal ChanezClinique des Bronches, Allergie et Sommeil/APHM, Marseille C2VN Center INSERM INRAE UMR1062, Aix-Marseille Université, Marseille, France.
Nadim CassirMicrobes, Evolution, Phylogeny and Infection (MEΦI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique - Hôpitaux de Marseille (AP-HM), Marseille, France.ORCID https://orcid.org/0000-0002-5276-6986
Assistance Publique Hôpitaux de Marseille · FRAix-Marseille Université · FRInserm · FRHôpital Nord · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a novel infectious disease caused by SARS-CoV-2 that emerged in late 2019 and which is now a pandemic. Solid organ transplant recipients are perceived to be at increased risk of severe COVID-19 due to their chronic use of immunosuppressive drugs (ISDs) and to their associated conditions. Scarce data are available on the optimized management of ISDs in these patients and on its impact on presentation, clinical course, viral shedding, and outcome. We report here two cases of COVID-19 in a cohabiting couple of lung transplant recipients for cystic fibrosis, who had different ISDs management and who developed discordant courses of their disease. Our findings suggest that the degree of their immunosuppression might be a reason for their different course and that ISDs might prove partially protective.

Indexed as

Lung TransplantationSARS-CoV-2Transplant RecipientsAdultCOVID-19FemaleHumansMaleCOVID-19cystic fibrosisimmunosuppressionlung transplantSARS-CoV-2viral pneumonia

Identifiers

PMID32654244
PMCPMC7404422
OpenAlexW3041925712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.