Evidence map›Paper›PMID 32653990›Full record

ArticleMycotoxin research2020

Subchronic exposure to individual and combined ochratoxin A and citrinin affects the expression of rat renal organic anion transporters.

Dean Karaica, Vedran Micek, Dubravka Rašić, Maja Peraica, Maja Šegvić Klarić, Davorka Breljak

Abstract read
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In one paragraph

Article in Mycotoxin research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dean KaraicaMolecular Toxicology Unit, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Zagreb, 10000, Croatia. dkaraica@imi.hr.ORCID https://orcid.org/0000-0001-8145-2786
Vedran MicekAnimal Breeding Unit, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Zagreb, 10000, Croatia.
Dubravka RašićToxicology Unit, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Zagreb, 10000, Croatia.
Maja PeraicaToxicology Unit, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Zagreb, 10000, Croatia.
Maja Šegvić KlarićDepartment of Microbiology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Schrottova 39/I kat, Zagreb, 10000, Croatia.
Davorka BreljakMolecular Toxicology Unit, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Zagreb, 10000, Croatia.
Institute for Medical Research and Occupational Health · HRUniversity of Zagreb · HR

Funding

Hrvatska Zaklada za Znanost IP-09-2014-5982
6 · The paper itself

Abstract

Ochratoxin A (OTA) and citrinin (CIT) are mycotoxins known to co-contaminate human/animal food/feed. Their prominent nephrotoxic effects pose a threat to human and animal health. Studies have shown synergistic or additive effects of these two mycotoxins, but a clear consensus on this phenomenon does not exist. In vitro/vivo studies on OTA and CIT effects showed they elevate oxidative stress parameters. Some in vitro studies tested resveratrol (RSV) as a potential antioxidant to counteract these OTA and CIT effects. However, data on the combined effects of OTA + CIT mycotoxins and RSV on their in vivo toxicity is lacking. We used immunofluorescence microscopy and Western blotting to study the subchronic effects of individual/combined OTA (0.125 and 0.250 mg kg

Indexed as

AnimalsCitrininKidneyMaleOchratoxinsOrganic Anion TransportersOxidative StressRatsRats, WistarCitrininochratoxin AOchratoxinsOrganic Anion TransportersKidneyMycotoxinsOral exposureOrganic anionsProximal tubulesResveratrol

Identifiers

PMID32653990
OpenAlexW3042150812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.