Evidence map›Paper›PMID 32653988›Full record

ArticleJapanese journal of radiology2020

Hippocampal sclerosis without visually detectable hippocampal MRI abnormalities: automated subfield volumetric analysis.

Hiromi Masaki, Keita Watanabe, Shingo Kakeda, Satoru Ide, Kohichiro Sugimoto, Issei Ueda, Toshihiko Hamamura, Sachi Hisanaga, Tomoko Toyota, Naoki Akamatsu and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Japanese journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Hiromi MasakiDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Keita WatanabeDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan. sapient@med.uoeh-u.ac.jp.ORCID http://orcid.org/0000-0001-9592-8802
Shingo KakedaDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Satoru IdeDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Kohichiro SugimotoDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Issei UedaDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Toshihiko HamamuraDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Sachi HisanagaDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Tomoko ToyotaDepartment of Neurology, University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan.
Naoki AkamatsuDepartment of Neurology, University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan.
Shohei ShimajiriDepartment of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Junkoh YamamotoDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japan.
Shigeru NishizawaDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japan.
Hiroaki AdachiDepartment of Neurology, University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan.
Yukunori KorogiDepartment of Radiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
University of Occupational and Environmental Health Japan · JPHirosaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to investigate hippocampal subfield volumes in patients with hippocampal sclerosis (HS) without visually detectable MRI abnormalities and to determine the diagnostic accuracy using hippocampal subfield volumes. MATERIALS AND

methodsWe examined 46 patients with unilateral HS who had a histopathological diagnosis, and 54 controls. The patients were divided into two groups; visually detectable HS (n = 26) and undetectable HS (n = 20) on MRI. The volumes of hippocampal subfield using FreeSurfer were compared among the three groups. Diagnostic accuracy was calculated as the AUC of ROC using cutoff values for each individual subfield.

resultsCompared with the controls, visually detectable HS showed significantly reduced volumes of all the hippocampal subfields and entire hippocampus, whereas visually undetectable HS showed significant atrophy only in the CA3 and hippocampus-amygdala-transition-area. To diagnose visually undetectable HS, the CA3 volumes had AUC of 0.719, which was higher than AUC of 0.614 based on the entire hippocampal volumes.

conclusionVisually undetectable HS demonstrated volume reductions in the CA3. Further, the CA3 volumes was more useful to diagnose visually undetectable HS compared with the entire hippocampal volumes.

Indexed as

AdultAtrophyEpilepsy, Temporal LobeFemaleHippocampusHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleOrgan SizeReproducibility of ResultsSclerosisEpilepsyHippocampal sclerosisHippocampal subfieldHippocampusMRI

Identifiers

PMID32653988
OpenAlexW3041016358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.