Evidence map›Paper›PMID 32653947›Full record

ArticleArchives of gynecology and obstetrics2020

Nausea and vomiting of pregnancy: associations with personal history of nausea and affected relatives.

Linda Laitinen, Miina Nurmi, Pauliina Ellilä, Päivi Rautava, Mari Koivisto, Päivi Polo-Kantola

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05788796 (The Effect of Band-Aid Applied to the Umbilical Area on Nausea and Vomiting During Pregnancy), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05788796 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Band-Aid Applied to the Umbilical Area on Nausea and Vomiting During Pregnancy

TypeinterventionalSponsorSakarya UniversityRan2023 to 2024Enrolled60ConditionsNausea Gravidarum, Vomiting of Pregnancy, Pregnancy Related, AcupressureArmsBand-aid application
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Linda LaitinenDepartment of Obstetrics and Gynecology, Central Finland Central Hospital, Keskussairaalantie 19, 40620, Jyväskylä, Finland. lmleht@utu.fi.ORCID 0000-0002-8589-4714
Miina NurmiDepartment of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0001-8186-4860
Pauliina ElliläDepartment of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0002-5634-7762
Päivi RautavaDepartment of Public Health, University of Turku, Turku, Finland.ORCID 0000-0003-2795-1327
Mari KoivistoTurku Clinical Research Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0002-6106-1427
Päivi Polo-KantolaDepartment of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0003-0665-0306
University of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine whether personal history of nausea or history of nausea and vomiting of pregnancy (NVP) in relatives are risk factors for a woman to suffer from NVP. Further, to evaluate if these factors are associated with the severity of NVP.

methodsCohort study of 2411 pregnant women recruited from maternity health care clinics. The severity of NVP was categorized according to Pregnancy-Unique Quantification of Emesis (PUQE) questionnaire into no/mild/moderate/severe NVP. History of nausea was assessed in connection with motion sickness, seasickness, migraine or other kinds of headache, after anesthesia, related to the use of contraceptives, and other kinds of nausea. History of NVP in relatives was categorized into first-degree (mother/sister) and second-degree relatives (more distant).

resultsIn multivariable analysis including previous personal history of nausea, motion sickness (OR 3.17, 95% CI 1.81-5.56, p < 0.0001) and nausea in migraine (OR 3.18, 95% CI 1.86-5.45, p < 0.0001) were associated with severe NVP. History of nausea in other kinds of headache was associated with moderate NVP (OR 1.91, 95% CI 1.34-2.72, p = 0.001). Women with affected first-degree relatives had higher odds for moderate (OR 3.84, 95% CI 2.72-5.40) and severe (OR 3.19, 95% CI 1.92-5.28) NVP (p < 0.0001). All these results remained significant after adjusting for parity, body mass index, smoking, employment and age.

conclusionWomen with personal history of nausea or family history of NVP have an increased susceptibility of NVP. This information is useful in pre-pregnancy counselling.

Indexed as

AdolescentAdultCohort StudiesFamilyFemaleHumansMiddle AgedNauseaPregnancyPregnancy ComplicationsRisk FactorsSurveys and QuestionnairesVomitingYoung AdultMigraineNausea and vomiting of pregnancyPregnancyPUQERelatives

Identifiers

PMID32653947
PMCPMC7471164
OpenAlexW3041300711

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.