ArticleNeurophysiologie clinique = Clinical neurophysiology2020
Electroencephalogram (EEG) in COVID-19: A systematic retrospective study.
Article in Neurophysiologie clinique = Clinical neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 11 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 11 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Neurological manifestations of COVID-19: a systematic review and detailed comprehension.The International journal of neuroscience · 2023Pooled it
- Imaging Markers of Neurologic Damage in COVID-19: A Systematic Review.Current medicinal chemistry · 2023Pooled it
- Database and AI Diagnostic Tools Improve Understanding of Lung Damage, Correlation of Pulmonary Disease and Brain Damage in COVID-19.Sensors (Basel, Switzerland) · 2022Pooled it
- Non-Invasive Multimodal Neuromonitoring in Non-Critically Ill Hospitalized Adult Patients With COVID-19: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2022Pooled it
- Meta-analysis of EEG findings in patients with COVID-19.Epilepsy & behavior : E&B · 2021Pooled it
- COVID-19, de novo seizures, and epilepsy: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Pooled it
- Pooled it
- Brain abnormalities in COVID-19 acute/subacute phase: A rapid systematic review.Brain, behavior, and immunity · 2020Pooled it
- Neurological Complications of COVID-19 and Possible Neuroinvasion Pathways: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Review
- EEG Signatures of COVID-19 Survival compared to close contacts and the Cuban EEG normative database.Clinical neurophysiology practice · 2026Article
- EEG signatures of cognitive decline after mild SARS-CoV-2 infection: an age-dependent study.BMC medicine · 2024Article
- Molecular cross-talk between long COVID-19 and Alzheimer's disease.GeroScience · 2024Review
- Article
- Neurological complications and effects of COVID-19: Symptoms and conceivable mechanisms.Brain hemorrhages · 2023Review
- [COVID-19: Neurological manifestations and complications during the acute phase of the disease].Bulletin de l'Academie nationale de medecine · 2023Review
- Study on brain damage patterns of COVID-19 patients based on EEG signals.Frontiers in human neuroscience · 2023Article
- The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review.Clinical neurophysiology practice · 2023Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAlthough rare, neurological manifestations in SARS-CoV-2 infection are increasingly being reported. We conducted a retrospective systematic study to describe the electroencephalography (EEG) characteristics in this disease, looking for specific patterns.
methodsEEGs performed in patients with positive PCR for SARS-CoV-2 between 25/03/2020 and 06/05/2020 in the University Hospital of Bicêtre were independently reviewed by two experienced neurologists. We used the American Clinical Neurophysiology Society's terminology for the description of abnormal patterns. EEGs were classified into five categories, from normal to critically altered. Interobserver reliability was calculated using Cohen's kappa coefficient. Medical records were reviewed to extract demographics, clinical, imaging and biological data.
resultsForty EEGs were reviewed in 36 COVID-19 patients, 18 in intensive care units (ICU) and 22 in medicine units. The main indications were confusion or fluctuating alertness for 23 (57.5%) and delayed awakening after stopping sedation in ICU in six (15%). EEGs were normal to mildly altered in 23 (57.5%) contrary to the 42.5% where EEG alterations were moderate in four (10%), severe in eight (20%) and critical in five (12.5%). Generalized periodic discharges (GPDs), multifocal periodic discharges (MPDs) or rhythmic delta activity (RDA) were found in 13 recordings (32.5%). EEG alterations were not stereotyped or specific. They could be related to an underlying morbid status, except for three ICU patients with unexplained encephalopathic features.
conclusionIn this first systematic analysis of COVID-19 patients who underwent EEG, over half of them presented a normal recording pattern. EEG alterations were not different from those encountered in other pathological conditions.
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