Evidence map›Paper›PMID 32652380›Full record

ArticleDrug and alcohol dependence2020

Substance use patterns and health profiles among US adults who use opioids, methamphetamine, or both, 2015-2018.

Riley D Shearer, Benjamin A Howell, Gavin Bart, Tyler N A Winkelman

Open access · hybridAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 112 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Riley D ShearerUniversity of Minnesota Medical School, 420 Delaware St SE, Mayo Building B681, Minneapolis, MN, 55455, USA. Electronic address: shear162@umn.edu.
Benjamin A HowellNational Clinician Scholars Program, Yale School of Medicine, 333 Cedar Street, Sterling Hall of Medicine I-456, New Haven, CT, 06520, USA; VA Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT, 06516, USA.
Gavin BartDivision of Addiction Medicine, Department of Medicine, Hennepin Healthcare, 914 S 8thSt, Shapiro 1.400, Minneapolis, MN, 55415 USA; Hennepin Healthcare Research Institute, 701 Park Ave., Suite PP7.700, Minneapolis, MN, 55415, USA.
Tyler N A WinkelmanHennepin Healthcare Research Institute, 701 Park Ave., Suite PP7.700, Minneapolis, MN, 55415, USA; Division of General Internal Medicine, Department of Medicine, Hennepin Healthcare, 716 S 7thSt, Minneapolis, MN, 55415, USA.
Hennepin Healthcare Research Institute · USUniversity of Minnesota Medical Center · USVA Connecticut Healthcare System · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008244 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHIMIZU, YOJI · 1988 to 2024
$13.6M
Yale Drug use, Addiction and HIV Research Scholars (DAHRS)K12DA033312 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Patrick O'Connor · 2013 to 2026
$7.2M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS K12 DA033312NIGMS NIH HHS T32 GM008244
6 · The paper itself

Abstract

backgroundMethamphetamine use, with and without opioids, has increased substantially, but little is known about the sociodemographic characteristics, substance use patterns, or health profiles of individuals who use methamphetamine. To design effective public health interventions, health care professionals and policymakers need data describing individuals who are using methamphetamine in the midst of the opioid crisis.

methodsWe used 2015-2018 data from the National Survey on Drug Use and Health and included non-elderly adults aged 18-64 years. We categorized respondents into three groups: use of opioids without methamphetamine use, use of methamphetamine without opioid use, or use of both opioids and methamphetamine. Multiple logistic regression models controlling for sociodemographic factors were used to compare substance use characteristics and measures of individual health between the three groups.

resultsPeople who used any methamphetamine were more likely to be unstably housed, low-income, and live in rural areas. Use of both opioids and methamphetamine was associated with a 132 % higher prevalence of injection needle use, and a nearly twofold higher prevalence of viral hepatitis compared with opioid use alone. One third of individuals reporting use of both opioids and methamphetamine had a severe mental illness, a 55 % higher prevalence than those using opioids alone.

conclusionsIndividuals who used opioids and methamphetamine had more complex substance use and health profiles than individuals who used opioids alone. These findings suggest public health and harm reduction approaches designed to address opioid use remain important in an era of rising methamphetamine use.

Indexed as

MethamphetamineAdolescentAdultAmphetamine-Related DisordersAnalgesics, OpioidFemaleHealth BehaviorHumansLogistic ModelsMaleMiddle AgedOpioid-Related DisordersPrevalenceUnited StatesYoung AdultAnalgesics, OpioidMethamphetamineHIV/AIDsMental illnessMethamphetamine useOpioid usePolysubstance use

Identifiers

PMID32652380
PMCPMC8147519
OpenAlexW3039468644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.