Evidence map›Paper›PMID 32652253›Full record

SynthesisAmerican journal of infection control2020

Decontamination and reuse of N95 filtering facemask respirators: A systematic review of the literature.

Carlos E Rodriguez-Martinez, Monica P Sossa-Briceño, Jorge A Cortés

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Demonstration of a Home Laundering Method for Cloth Facepieces to Achieve Hygienic and Sustainable Reuse.New solutions : a journal of environmental and occupational health policy : NS · 2025
    Article
  7. Article
  8. Deposition of Pd, Pt, and PdPt Nanoparticles on TiOMolecules (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Article
  11. Article
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  13. Article
  14. Article
  15. Article
  16. Large-scale decontamination of disposable FFP2 and FFP3 respirators by hydrogen peroxide vapour, Finland, April to June 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  17. Article
  18. Article
  19. Effective inactivation ofJournal of analytical science and technology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carlos E Rodriguez-MartinezDepartment of Pediatrics, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia; Department of Pediatric Pulmonology and Pediatric Critical Care Medicine, School of Medicine, Universidad El Bosque, Bogota, Colombia. Electronic address: carerodriguezmar@unal.edu.co.
Monica P Sossa-BriceñoDepartment of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia; Scientific Direction, Clínica de Marly Jorge Cavelier Gaviria, Avenida Paseo los Zipas, Chía, Colombia.
Jorge A CortésDepartment of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAs has happened in other emerging respiratory pandemics, demand for N95 filtering facemask respirators (FFRs) has far exceeded their manufacturing production and availability in the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. One of the proposed strategies for mitigating the massive demand for N95 FFRs is their reuse after a process of decontamination that allows the inactivation of any potentially infectious material on their surfaces. This article aims to summarize all of the available evidence on the different decontamination methods that might allow disposable N95 FFRs to be reused, with emphasis on decontamination from SARS-CoV-2.

methodsWe performed a systematic review of the literature in order to identify studies reporting outcomes of at least 1 decontamination method for inactivating or removing any potentially infectious material from the surface of N95 FFRs, specifically addressing issues related to reduction of the microbial threat (including SARS-CoV-2 when available), maintaining the function of N95 FFRs and a lack of residual toxicity.

resultsWe identified a total of 15 studies reporting on the different decontamination methods that might allow disposable N95 FFRs to be reused, including small-scale energetic methods and disinfecting solutions/spray/wipes. Among these decontamination methods, ultraviolet germicidal irradiation and vaporized hydrogen peroxide seem to be the most promising decontamination methods for N95 FFRs, based on their biocidal efficacy, filtration performance, fitting characteristics, and residual chemical toxicity, as well as other practical aspects such as the equipment required for their implementation and the maximum number of decontamination cycles.

conclusionsAlthough all the methods for the decontamination and reuse of N95 FFRs have advantages and disadvantages, ultraviolet germicidal irradiation and vaporized hydrogen peroxide seem to be the most promising methods.

Indexed as

Equipment ReuseCOVID-19DecontaminationHumansMasksN95 RespiratorsSARS-CoV-2DisinfectionEquipment reuseMicrobial viabilityRespiratory protective devicesVirus inactivation

Identifiers

PMID32652253
PMCPMC7342027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.