Evidence map›Paper›PMID 32651998›Full record

Trial reportThe American journal of clinical nutrition2020

Maternal dietary diversity and dietary quality scores in relation to adverse birth outcomes in Tanzanian women.

Isabel Madzorera, Sheila Isanaka, Molin Wang, Gernard I Msamanga, Willy Urassa, Ellen Hertzmark, Christopher Duggan, Wafaie W Fawzi

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00197548 (A Trial of Micronutrients and Adverse Pregnancy Outcomes), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00197548 phase3completednot on this map

A Trial of Micronutrients and Adverse Pregnancy Outcomes

TypeinterventionalSponsorHarvard School of Public Health (HSPH)Ran2001 to 2006Enrolled8,468ConditionsPregnancy, Premature Birth, Infant, Low Birth Weight, Pregnancy OutcomesArmsMultivitamins-vitamins B-complex, C, and E, Placebo
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Isabel MadzoreraDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Sheila IsanakaDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Molin WangDepartments of Epidemiology and Biostatistics, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Gernard I MsamangaMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Willy UrassaMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Ellen HertzmarkDepartment of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.
Christopher DugganDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Wafaie W FawziDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Harvard University · USMuhimbili University of Health and Allied Sciences · TZBoston Children's Hospital · USBrigham and Women's Hospital · USHarvard Global Health Institute · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
Patient-oriented Research in Pediatric Diarrheal DiseasesK24DK104676 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI DUGGAN, CHRISTOPHER P · 2015 to 2019
$903k
NIDDK NIH HHS K24 DK104676NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

backgroundPreterm birth (PTB), small for gestational age (SGA), and low birth weight (LBW) are risk factors for morbidity and mortality among infants. High-quality maternal diets during pregnancy may protect against these adverse birth outcomes.

objectivesThe aim of this study was to prospectively examine the association of maternal dietary diversity and quality during pregnancy with birth outcomes among women in Dar es Salaam, Tanzania.

methodsWe analyzed data from 7553 HIV-negative pregnant women enrolled in a multivitamin trial at 12-27 weeks of gestation. Dietary intake was assessed using 24-h dietary recalls. Dietary diversity scores (DDS; range: 0-10) were computed as the number of food groups consumed by women, using FAO's Minimum Dietary Diversity for Women index. The Prime Diet Quality Score (PDQS; range: 0-42) assessed maternal diet quality based on consumption of 21 healthy and unhealthy food groups. Log binomial regression methods were used to assess associations of DDS and PDQS with PTB, SGA, LBW, and fetal loss.

resultsIn the previous 24 h, 99.9% of all women had consumed cereal and staples, 57.9% meats, 4.7% eggs, and 0.5% nuts and seeds. Median DDS was 3.0 (IQR: 2.5-3.5). For the PDQS, all women consumed ≥4 servings/wk of green leafy vegetables and refined grains. Higher DDS was associated with lower risk of SGA (RR highest compared with lowest quintile: 0.74; 95% CI: 0.62, 0.89). Higher PDQS was associated with lower risk of PTB (RR highest compared with lowest quintile: 0.55; 95% CI: 0.46, 0.66), LBW (RR: 0.53; 95% CI: 0.40, 0.70), and fetal loss (RR: 0.53; 95% CI, 0.34, 0.82).

conclusionsPDQS was inversely associated with PTB, LBW, and fetal loss, and DDS was inversely associated with SGA. These findings suggest that in addition to dietary diversity, diet quality should be considered as important in understanding dietary risk factors for poor birth outcomes.This trial was registered at clinicaltrials.gov as NCT00197548.

Indexed as

Pregnancy OutcomePrenatal Nutritional Physiological PhenomenaAdultDietDietary SupplementsDouble-Blind MethodFemaleHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgePregnancyPremature BirthPrenatal CareTanzaniaVitaminsVitaminsdietary diversityfetal losslow birth weightMinimum Dietary Diversity for Womenpregnancy outcomespretermPrime Diet Quality Scoresmall for gestational ageTanzania

Identifiers

PMID32651998
PMCPMC7458779
OpenAlexW3040852974

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.