Evidence map›Paper›PMID 32651861›Full record

SynthesisSports medicine (Auckland, N.Z.)2020

Occupational Physical Activity and Lung Cancer Risk: A Systematic Review and Meta-Analysis.

Benny Rana, Liang Hu, Andrew Harper, Chao Cao, Cheryl Peters, Darren Brenner, Lin Yang

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Update on Occupational Cancer for Better Cancer Prevention and Control.Asian Pacific journal of cancer prevention : APJCP · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Etiology of lung cancer: Evidence from epidemiologic studies.Journal of the National Cancer Center · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Benny RanaDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, 5th Floor, Holy Cross Centre, Box ACB, 2210-2 St. SW, Calgary, AB, T2S 3C3, Canada.
Liang HuDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, 5th Floor, Holy Cross Centre, Box ACB, 2210-2 St. SW, Calgary, AB, T2S 3C3, Canada.
Andrew HarperDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, 5th Floor, Holy Cross Centre, Box ACB, 2210-2 St. SW, Calgary, AB, T2S 3C3, Canada.
Chao CaoProgram in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Cheryl PetersDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, 5th Floor, Holy Cross Centre, Box ACB, 2210-2 St. SW, Calgary, AB, T2S 3C3, Canada.
Darren BrennerDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, 5th Floor, Holy Cross Centre, Box ACB, 2210-2 St. SW, Calgary, AB, T2S 3C3, Canada.
Lin YangDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, 5th Floor, Holy Cross Centre, Box ACB, 2210-2 St. SW, Calgary, AB, T2S 3C3, Canada. lin.yang@ahs.ca.ORCID http://orcid.org/0000-0002-1698-6666
Alberta Health Services · CAWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo deliver a systematic review of the literature synthesizing data on the association of occupational physical activity with lung cancer risk in observational studies.

designSystematic review with meta-analysis. DATA SOURCE: A literature search was performed in the electronic databases of PubMed/Medline and Embase. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: We screened peer-reviewed articles from prospective cohort and case-control studies assessing the association of occupational physical activity with lung cancer risk. A sex-specific meta-analysis assessed the association of high (compared to low/sedentary) level occupational physical activity with lung cancer risk, estimating the relative risk (RR) and odds ratio (OR) with a 95% confidence interval (CI).

resultsThe systematic search identified 2065 articles, among which, eight journal articles met the inclusion criteria. The meta-analysis adjusted for age, smoking status and/or intensity, with a pooled sample size of 532,282 participants (men: 219,410; women: 312,872). A random-effect model of four prospective and four case-control studies indicated that men who engage in high-level occupational physical activity had a 15% higher risk (OR 1.15, 95% CI 1.04-1.28) of lung cancer than those engaging in low/sedentary-level occupational physical activity. There was no association observed among women (OR = 1.01, 95% CI 0.77-1.34) based on three available studies (prospective cohort: n = 2; case-control: n = 1).

conclusionsFindings from the review suggest a higher risk of lung cancer among men reporting high-level occupational physical activity. Further prospective studies incorporating rigorous measures of domain-specific physical activity, detailed smoking status and intensity, and other occupational exposures are needed to elucidate this association. PROSPERO REGISTRATION ID: CRD42019137911.

Indexed as

ExerciseLung NeoplasmsOccupational HealthFemaleHumansMaleProspective StudiesRisk Factors

Identifiers

PMID32651861
OpenAlexW3040899208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.