ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Regadenoson versus dipyridamole: Evaluation of stress myocardial blood flow response on a CZT-SPECT camera.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- The Incremental Role of Stress Echocardiography in Valvular Heart Disease: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Measuring myocardial blood flow using dynamic myocardial perfusion SPECT: artifacts and pitfalls.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- A preliminary study of dobutamine myocardial flow reserve onAnnals of nuclear medicine · 2023Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Myocardial flow reserve estimation with contemporary CZT-SPECT andJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- High technology by CZT cameras: It is time to join forces.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Myocardial blood flow is the dominant factor influencing cardiac magnetic resonance adenosine stress T2.NMR in biomedicine · 2022Article
- Expanding the repertoire of methanocarba nucleosides from purinergic signaling to diverse targets.RSC medicinal chemistry · 2021Review
- Myocardial Flow Reserve Measurement During CZT-SPECT Perfusion Imaging for Coronary Artery Disease Screening: Correlation With Clinical Findings and Invasive Coronary Angiography-The CFR-OR Study.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRegadenoson is a selective adenosine receptor agonist. It is currently unclear if the level of hyperemia differs between stress agents. We compared Myocardial Blood Flow (MBF) and Myocardial Flow Reserve (MFR) response on CZT-SPECT Myocardial Perfusion Imaging (MPI) to evaluate if dipyridamole and regadenoson could induce the same level of hyperemia.
methods228 patients with dynamic CZT-SPECT MPI were retrospectively analyzed (66 patients stressed with regadenoson and 162 with dipyridamole) in terms of MBF and MFR. To rule out confounding factors, two groups of 41 patients were matched for clinical characteristics in a sub-analysis, excluding high cardiovascular risk patients.
resultsOverall stress MBF was higher in regadenoson patients (1.71 ± 0.73 vs. 1.44 ± 0.55 mL·min
conclusionsOur results suggest that dipyridamole and regadenoson induce equivalent hyperemia in dynamic SPECT with similar stress MBF and MFR in comparable patients.
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