Evidence map›Paper›PMID 32651762›Full record

ArticleAIDS and behavior2021

Development and Validation of a Sociodemographic and Behavioral Characteristics-Based Risk-Score Algorithm for Targeting HIV Testing Among Adults in Kenya.

Hellen Muttai, Bernard Guyah, Paul Musingila, Thomas Achia, Fredrick Miruka, Stella Wanjohi, Caroline Dande, Polycarp Musee, Fillet Lugalia, Dickens Onyango and 8 more

Abstract readValidation Study
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  9. Developing HIV risk prediction tools in four African settings.Tropical medicine & international health : TM & IH · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Hellen MuttaiDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya. hoz1@cdc.gov.ORCID http://orcid.org/0000-0003-1598-6418
Bernard GuyahSchool of Public Health, Maseno University, Kisumu, Kenya.
Paul MusingilaDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya.
Thomas AchiaDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya.
Fredrick MirukaDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya.
Stella WanjohiCenter for Health Solution, Kisumu, Kenya.
Caroline DandeUniversity of California at San Francisco, Kisumu, Kenya.
Polycarp MuseeElizabeth Glaser Pediatric AIDS Foundation, Homa Bay, Kenya.
Fillet LugaliaColumbia University, Kisumu, Kenya.
Dickens OnyangoKisumu County Department of Health, Kisumu, Kenya.
Eunice KinywaKisumu County Department of Health, Kisumu, Kenya.
Gordon OkomoHoma Bay County Department of Health, Homa Bay, Kenya.
Iscah MothHoma Bay County Department of Health, Homa Bay, Kenya.
Samuel OmondiSiaya County Department of Health, Siaya, Kenya.
Caren AyiekoSiaya County Department of Health, Siaya, Kenya.
Lucy NgangaDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya.
Rachael H JosephDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya.
Emily Zielinski-GutierrezDivision of Global HIV & TB (DGHT), United States Centers for Disease Control and Prevention (CDC), Kenya, KEMRI Campus, P.O. Box 606, Nairobi, 00621, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To inform targeted HIV testing, we developed and externally validated a risk-score algorithm that incorporated behavioral characteristics. Outpatient data from five health facilities in western Kenya, comprising 19,458 adults ≥ 15 years tested for HIV from September 2017 to May 2018, were included in univariable and multivariable analyses used for algorithm development. Data for 11,330 adults attending one high-volume facility were used for validation. Using the final algorithm, patients were grouped into four risk-score categories: ≤ 9, 10-15, 16-29 and ≥ 30, with increasing HIV prevalence of 0.6% [95% confidence interval (CI) 0.46-0.75], 1.35% (95% CI 0.85-1.84), 2.65% (95% CI 1.8-3.51), and 15.15% (95% CI 9.03-21.27), respectively. The algorithm's discrimination performance was modest, with an area under the receiver-operating-curve of 0.69 (95% CI 0.53-0.84). In settings where universal testing is not feasible, a risk-score algorithm can identify sub-populations with higher HIV-risk to be prioritized for HIV testing.

Indexed as

HIV InfectionsHIV TestingAdultAlgorithmsDemographyHumansKenyaRisk FactorsSocioeconomic FactorsHIV testingKenyaRisk-score algorithm

Identifiers

PMID32651762
PMCPMC7846530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.