ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020
Clinical features in 52 patients with COVID-19 who have increased leukocyte count: a retrospective analysis.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 83 citations in OpenAlex.
- Mortality Due to Covid-19 in Hospitalized Patients: A Prediction Model Based on Different Risk Factors.Risk management and healthcare policy · 2025Article
- Inflammatory, Hematological, and Biochemical Biomarkers in COVID-19 Patients.Immunity, inflammation and disease · 2024Article
- Acute Kidney Injury in the Context of COVID-19: An Analysis in Hospitalized Mexican Patients.Infectious disease reports · 2024Article
- Interpretable Machine Learning for COVID-19: An Empirical Study on Severity Prediction Task.IEEE transactions on artificial intelligence · 2023Article
- Impact of comorbidities on hospitalised Syrian patients with COVID-19: a retrospective study.BMJ open · 2023Article
- Impact of an Early Warning System Protocol, for Patients Admitted to the Medical Floors with SARS-COV2 Pneumonia, on ICU Admission.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2023Article
- Dynamic alterations in white blood cell counts and SARS-CoV-2 shedding in saliva: an infection predictor parameter.Frontiers in medicine · 2023Article
- Hematological parameters and their predictive value for assessing disease severity in laboratory-confirmed COVID-19 patients: a retrospective study.American journal of blood research · 2023Article
- The Impact of Clostridioides Difficile Infection in Hospitalized Patients: What Changed during the Pandemic?Diagnostics (Basel, Switzerland) · 2022Article
- Haematological profile abnormalities; and its relationship with severity and outcome of COVID-19 infection.African health sciences · 2022Article
- Predictors and microbiology of respiratory and bloodstream bacterial infection in patients with COVID-19: living rapid review update and meta-regression.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022Review
- Pathological effects of SARS-CoV-2 on hematological and immunological cells: Alterations in count, morphology, and function.Pathology, research and practice · 2022Review
- Role of SARS-CoV-2 -induced cytokines and growth factors in coagulopathy and thromboembolism.Cytokine & growth factor reviews · 2022Review
- The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders.Biochemical pharmacology · 2022Review
- The health facility as a risk factor for multidrug-resistant gram-negative bacteria in critically ill patients with COVID-19.Clinics (Sao Paulo, Brazil) · 2022Article
- Neurological manifestations of COVID-19 in patients: from path physiology to therapy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Review
- Association of HScore Parameters with Severe COVID-19: A Systematic Review and Meta-Analysis.Iranian journal of medical sciences · 2021Review
- Scat-NET: COVID-19 diagnosis with a CNN model using scattergram images.Computers in biology and medicine · 2021Article
- Correlation of hematological parameters and cycle threshold in ambulatory patients with SARS-CoV-2 infection.International journal of laboratory hematology · 2021Article
- Role of laboratory biomarkers in assessing the severity of COVID-19 disease. A cross-sectional study.Journal of family medicine and primary care · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent reports have showed that a proportion of patients with Coronavirus Disease 2019 (COVID-19) presented elevated leukocyte count. Clinical data about these patients is scarce. We aimed to evaluate the clinical findings of patients with COVID-19 who have increased leukocyte at admission. We retrospectively collected the clinical data on the 52 patients who have increased leukocyte count at admission from the 619 patients with confirmed COVID-19 who had pneumonia with abnormal features on chest CT scan in Renmin Hospital of Wuhan University in Wuhan, China, from February 3 to March 3, 2020. The mean age of the 52 patients with increased leukocyte count was 64.7 (SD 11.4) years, 32 (61.5%) were men and 47 (90.4%) had fever. Compared with the patients with non-increased leukocyte count, the patients with increased leukocyte count were significantly older (P < 0.01), were more likely to have underlying chronic diseases (P < 0.01), more likely to develop critically illness (P < 0.01), more likely to admit to an ICU (P < 0.01), more likely to receive mechanical ventilation (P < 0.01), had higher rate of death (P < 0.01) and the blood levels of neutrophil count and the serum concentrations of CRP and IL-6 were significantly increased, (P < 0.01). The older patients with COVID-19 who had underlying chronic disorders are more likely to develop leukocytosis. These patients are more likely to develop critical illness, with a high admission to an ICU and a high mortality rate.
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