ReviewHypertension research : official journal of the Japanese Society of Hypertension2020
Frailty and hypertension in older adults: current understanding and future perspectives.
Review in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Interplay between frailty and cardiometabolic disorders: from pathophysiology to clinical implications.Cardiovascular diabetology · 2025Pooled it
- Global Prevalence and Factors Associated with Frailty among Community-Dwelling Older Adults with Hypertension: A Systematic Review and Meta-Analysis.The journal of nutrition, health & aging · 2023Pooled it
- Frailty prediction in heart failure patients with acute infections: the potential role of thiazide diuretics?PloS one · 2026Article
- The relationship between cognitive function and quality of life in older hypertension patients: a parallel mediation effect of frailty and medication discrepancies.BMC geriatrics · 2025Article
- Association of hemoglobin glycation index with frailty and all-cause mortality in hypertensive patients.Diabetology & metabolic syndrome · 2025Article
- Association between frailty with kidney stones disease among adults aged 20 years and older population: a cross-sectional study of NHANES 2007-2020.European journal of medical research · 2025Article
- Burden of heart failure attributable to chronic kidney disease in older adults (1990-2021): an analysis from the global burden of disease study.Frontiers in public health · 2025Article
- Frailty and comorbidity in older adults with and without diabetes and chronic leg ulcer: A cross-sectional study.International wound journal · 2025Article
- Frailty and chronic diseases: A bi-directional relationship.Aging medicine (Milton (N.S.W)) · 2024Review
- Genetically determined blood pressure, antihypertensive drug classes, and frailty: A Mendelian randomization study.Aging cell · 2024Article
- Association of frailty status with overall survival in elderly hypertensive patients: based on the Chinese Longitudinal Healthy Longevity Survey.BMC public health · 2024Article
- Associations among frailty status, hypertension, and fall risk in community-dwelling older adults.International journal of nursing sciences · 2024Article
- Correlates of Frailty in Hospitalized Older Adults with Hypertension and Its Influence on Clinical Prognosis.International journal of general medicine · 2024Article
- Current topics of frailty in association with hypertension and other medical conditions.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Prevalence of Hypertension and Its Association with Cardiovascular Risk Factors in College Students in Hunan, China.International journal of general medicine · 2023Article
- Self-Organizing Maps to Multidimensionally Characterize Physical Profiles in Older Adults.International journal of environmental research and public health · 2022Article
- Prevalence of pain in community-dwelling older adults with hypertension in the United States.Scientific reports · 2022Article
- Hypertension, the decline of activities of daily living (ADL) and frailty.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Review
- Frailty-aware care: giving value to frailty assessment across different healthcare settings.BMC geriatrics · 2022Review
- Systolic Blood Pressure and Mortality in Community-Dwelling Older Adults: The Role of Frailty.The journal of nutrition, health & aging · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is an important factor affecting the health of older adults. Antihypertensives can reduce stroke, cardiovascular events, and mortality in older hypertensive patients. Blood pressure management is difficult in older adults since geriatric syndromes such as frailty and comorbidities often coexist with hypertension. Recent guidelines propose taking functional status into account when targeting blood pressure in older people. Therefore, a better understanding and control of frailty risk factors could improve the prognosis of older adults with hypertension. However, there are relatively few studies on hypertension and frailty in older adults, especially studies focused on antihypertensive treatment. The goals, target values, and choice of antihypertensive treatment for frail older adults are still disputed. We reviewed the recent literature focusing on frailty and hypertension in older adults and propose a management process for screening and assessing frailty and hypertension before the use of antihypertensives. The process can support older adults with lifestyle interventions and frailty management and help them begin taking a single antihypertensive medication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.