ArticleScientific reports2020
Increased large-scale inter-network connectivity in relation to impulsivity in Parkinson's disease.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Imaging Cognitive Impairment and Impulse Control Disorders in Parkinson's Disease.Frontiers in neurology · 2021Pooled it
- Multimodal objective assessment of impulsivity in healthy and mood disorder participants.NPP - digital psychiatry and neuroscience · 2025Article
- Time-varying brain state dynamics in trait impulsivity and anxiety: An HSMM analysis of resting-state fMRI.Social cognitive and affective neuroscience · 2025Article
- Charting the brain networks of impulsivity: Meta-analytic synthesis, functional connectivity modelling, and neurotransmitter associations.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Impulsivity Traits in Parkinson's Disease: A Systematic Review and Meta-Analysis.Movement disorders clinical practice · 2023Review
- Altered resting-state functional connectivity within corticostriatal and subcortical-striatal circuits in chronic pain.Scientific reports · 2022Article
- The roles of behavioral inhibition/activation systems and impulsivity in problematic smartphone use: A network analysis.Frontiers in public health · 2022Article
- A single-arm open-label pilot study of brief mindfulness meditation to control impulsivity in Parkinson's disease.PloS one · 2022Article
- Applying network analysis to understand the relationships between impulsivity and social media addiction and between impulsivity and problematic smartphone use.Frontiers in psychiatry · 2022Article
- Functional Connectome in Parkinson's Disease and Parkinsonism.Current neurology and neuroscience reports · 2021Review
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Impulsivity is a neuropsychiatric feature of Parkinson's disease (PD). We investigated the pathophysiology of impulsivity in PD using resting-state functional magnetic resonance imaging (rs-fMRI). We investigated 45 patients with idiopathic PD and 21 healthy controls. Based on Barratt Impulsiveness Scale (BIS-11) score, PD patients were classified as higher (PD-HI) or lower impulsivity (PD-LI). Functional connectivity (FC) between various large-scale brain networks were analysed using the CONN toolbox. FC between the right frontoparietal network (FPN) and medial visual network (MVN) was significantly higher in PD-HI patients than PD-LI patients (false discovery rate [FDR]-adjusted p = 0.0315). FC between the right FPN and MVN had a significant positive correlation with total BIS-11 score (FDR-adjusted p = 0.010) and the attentional impulsivity (FDR-adjusted p = 0.046) and non-planning impulsivity subscale scores (FDR-adjusted p = 0.018). On the other hand, motor impulsivity subscale score had a significant negative correlation with the FC between the default-mode and salience networks (right supramarginal gyrus, FDR-adjusted p = 0.018; anterior cingulate cortex, FDR-adjusted p = 0.027); this trend was observed in healthy controls. The attentional and non-planning impulsivity, regarded as 'cognitive' impulsivity, may be associated with dysfunction in integration of perceptual information and flexible cognitive control in PD.
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