Evidence map›Paper›PMID 32651339›Full record

ReviewJournal of vestibular research : equilibrium & orientation2020

The vestibular implant: Opinion statement on implantation criteria for research.

Raymond van de Berg, Angel Ramos, Vincent van Rompaey, Alexandre Bisdorff, Angelica Perez-Fornos, Jay T Rubinstein, James O Phillips, Michael Strupp, Charles C Della Santina, Nils Guinand

Erratum issued Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of vestibular research : equilibrium & orientation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04918745 (VertiGO! - Get up and GO! With the Vestibular Implant), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04918745 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

VertiGO! - Get up and GO! With the Vestibular Implant

TypeinterventionalSponsorMaastricht University Medical CenterRan2021 to 2029Enrolled13ConditionsBilateral Vestibular LossArmsCochlear Vestibular Implant (CVI)
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Vestibular implant stimulation can improve self-motion perception.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Vestibular electrode position stability over time.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Next Challenges of Vestibular Implantation in Humans.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Review
  17. Vestibular prosthesis: from basic research to clinics.Frontiers in integrative neuroscience · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 7 countries.

Raymond van de BergDepartment of Otorhinolaryngology and Head & Neck Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.
Angel RamosDepartment of Otolaryngology Head Neck Surgery. Complejo Hospitalario Universitario Insular Materno Infantil de Gran Canaria. Department of Otolaryngology. Las Palmas University. (ULPGC). Psychoacoustic & Equilibrium Laboratory. Las Palmas University (ULPGC).
Vincent van RompaeyDepartment of Otorhinolaryngology and Head & Neck Surgery, Antwerp University Hospital, Department of Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Belgium.
Alexandre BisdorffClinique du Vertige, Centre Hospitalier Emile Mayrisch, Esch-sur-Alzette, Luxembourg.
Angelica Perez-FornosDivision of Otorhinolaryngology Head and Neck Surgery, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Jay T RubinsteinOtolaryngology-HNS, Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, USA.
James O PhillipsOtolaryngology-HNS, Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, USA.
Michael StruppDepartment of Neurology and German Center for Vertigo and Balance Disorders, Ludwig Maximilians University, Munich, Germany.
Charles C Della SantinaDepartments of Otolaryngology - Head & Neck Surgery and Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Nils GuinandDivision of Otorhinolaryngology Head and Neck Surgery, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
University of Geneva · CHUniversity of Washington · USCentre Hospitalier de Luxembourg · LUGerman Center for Lung Research · DEJohns Hopkins University · USNational Research Tomsk State University · RUUniversity of Antwerp · BE

Funding

Optimization of a human vestibular prosthesisR01DC014002 · NIDCD · UNIVERSITY OF WASHINGTON · PI RUBINSTEIN, JAY T. · 2014 to 2018
$2.9M
NIDCD NIH HHS R01 DC014002
6 · The paper itself

Abstract

This opinion statement proposes a set of candidacy criteria for vestibular implantation of adult patients with bilateral vestibulopathy (BVP) in a research setting. The criteria include disabling chronic symptoms like postural imbalance, unsteadiness of gait and/or head movement-induced oscillopsia, combined with objective signs of reduced or absent vestibular function in both ears. These signs include abnormal test results recorded during head impulses (video head impulse test or scleral coil technique), bithermal caloric testing and rotatory chair testing (sinusoidal stimulation of 0.1 Hz). Vestibular implant (VI) implantation criteria are not the same as diagnostic criteria for bilateral vestibulopathy. The major difference between VI-implantation criteria and the approved diagnostic criteria for BVP are that all included vestibular tests of semicircular canal function (head impulse test, caloric test, and rotatory chair test) need to show significant impairments of vestibular function in the implantation criteria. For this, a two-step paradigm was developed. First, at least one of the vestibular tests needs to fulfill stringent criteria, close to those for BVP. If this is applicable, then the other vestibular tests have to fulfill a second set of criteria which are less stringent than the original criteria for BVP. If the VI-implantation is intended to excite the utricle and/or saccule (otolith stimulation), responses to cervical and ocular vestibular evoked myogenic potentials must be absent in addition to the above mentioned abnormalities of semicircular canal function. Finally, requirements for safe and potentially effective stimulation should be met, including implanting patients with BVP of peripheral origin only, and assessing possible medical and psychiatric contraindications.

Indexed as

Bilateral VestibulopathyBiomedical ResearchCaloric TestsCochlear ImplantsHead Impulse TestHumansSocieties, MedicalVestibular Function TestsVestibule, Labyrinthbilateral vestibular areflexiabilateral vestibular hypofunctionbilateral vestibular lossbilateral vestibulopathyelectrical stimulationimplantation criteriaVestibular implantvestibular prosthesisvestibular systemvestibulo-ocular reflexVOR

Identifiers

PMID32651339
PMCPMC9249290
OpenAlexW3041890918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.