Evidence map›Paper›PMID 32650817›Full record

SynthesisAddiction science & clinical practice2020

Assessing the readiness of digital data infrastructure for opioid use disorder research.

Arjun Venkatesh, Caitlin Malicki, Kathryn Hawk, Gail D'Onofrio, Jeremiah Kinsman, Andrew Taylor

Abstract readSystematic Review
In one paragraph

Synthesis in Addiction science & clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Identifying Opioid Overdose and Opioid Use Disorder and Related Information from Clinical Narratives Using Large Language Models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025
    Article
  6. Article
  7. Article
  8. Redesign of Opioid Use Disorder Screening and Treatment in the ED.NEJM catalyst innovations in care delivery · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Providers' Perceptions of the Effectiveness of Electronic Health Records in Identifying Opioid Misuse.Journal of healthcare management / American College of Healthcare Executives
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arjun VenkateshDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA. arjun.venkatesh@yale.edu.ORCID 0000-0002-8248-0567
Caitlin MalickiDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Kathryn HawkDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Gail D'OnofrioDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Jeremiah KinsmanDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Andrew TaylorDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
Yale University Clinical and Translational Science Award ProgramKL2TR000140 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$2.9M
NCATS NIH HHS KL2 TR000140NIDA NIH HHS UG1 DA015831
6 · The paper itself

Abstract

backgroundGaps in electronic health record (EHR) data collection and the paucity of standardized clinical data elements (CDEs) captured from electronic and digital data sources have impeded research efforts aimed at understanding the epidemiology and quality of care for opioid use disorder (OUD). We identified existing CDEs and evaluated their validity and usability, which is required prior to infrastructure implementation within EHRs.

methodsWe conducted (a) a systematic literature review of publications in Medline, Embase and the Web of Science using a combination of at least one term related to OUD and EHR and (b) an environmental scan of publicly available data systems and dictionaries used in national informatics and quality measurement of policy initiatives. Opioid-related data elements identified within the environmental scan were compared with related data elements contained within nine common health data code systems and each element was graded for alignment with match results categorized as "exact", "partial", or "none."

resultsThe literature review identified 5186 articles for title search, of which 75 abstracts were included for review and 38 articles were selected for full-text review. Full-text articles yielded 237 CDEs, only 12 (5.06%) of which were opioid-specific. The environmental scan identified 379 potential data elements and value sets across 9 data systems and libraries, among which only 84 (22%) were opioid-specific. We found substantial variability in the types of clinical data elements with limited overlap and no single data system included CDEs across all major data element types such as substance use disorder, OUD, medication and mental health. Relative to common health data code systems, few data elements had an exact match (< 1%), while 61% had a partial match and 38% had no matches.

conclusionsDespite the increasing ubiquity of EHR data standards and national attention placed on the opioid epidemic, we found substantial fragmentation in the design and construction of OUD related CDEs and little OUD specific CDEs in existing data dictionaries, systems and literature. Given the significant gaps in data collection and reporting, future work should leverage existing structured data elements to create standard workflow processes to improve OUD data capture in EHR systems.

Indexed as

Health Services ResearchData CollectionElectronic Health RecordsHumansOpioid-Related DisordersQuality of Health CareCommon data elementsElectronic health recordsEmergency medicineOpioid-related disorders

Identifiers

PMID32650817
PMCPMC7350566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.