ArticleBMC geriatrics2020
Protocol for understanding acute sarcopenia: a cohort study to characterise changes in muscle quantity and physical function in older adults following hospitalisation.
Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03858192 (Understanding Acute Sarcopenia), which is not on this map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Understanding Acute Sarcopenia: a Time-limited Cohort Study to Characterise Changes in Muscle Mass and Physical Function in Older Adults Following Hospitalisation
Who cites it
13 citing papers in PubMed.
- Dynamic muscle loss and metabolic dysregulation in sepsis-associated muscle wasting: an integrated ultrasound and metabolomics study.Frontiers in medicine · 2026Article
- Acute Sarcopenia: Mechanisms and Management.Nutrients · 2024Review
- The relation between preoperative radiological sarcopenia and postoperative recovery of physical activity in older surgical cancer patients; an explorative study.The journal of nutrition, health & aging · 2024Observational
- Establishing Predictors of Acute Sarcopenia: A Proof-Of-Concept Study Utilising Network Analysis.Aging and disease · 2024Observational
- Abdominal Body Composition Reference Ranges and Association With Chronic Conditions in an Age- and Sex-Stratified Representative Sample of a Geographically Defined American Population.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Investigating the impact of fluid status on the ultrasound assessment of muscle quantity and quality in the diagnosis of sarcopenia - a multidimensional cross-sectional study.BMC geriatrics · 2023Article
- Acute skeletal muscle loss in SARS-CoV-2 infection contributes to poor clinical outcomes in COVID-19 patients.Journal of cachexia, sarcopenia and muscle · 2022Article
- Induced frailty and acute sarcopenia are overlapping consequences of hospitalisation in older adults.Journal of frailty, sarcopenia and falls · 2022Article
- Trajectories of muscle quantity, quality and function measurements in hospitalized older adults.Geriatrics & gerontology international · 2022Article
- The feasibility of conducting acute sarcopenia research in hospitalised older patients: a prospective cohort study.European geriatric medicine · 2022Article
- Post-COVID-19 acute sarcopenia: physiopathology and management.Aging clinical and experimental research · 2021Review
- Muscle quantity and function measurements are acceptable to older adults during and post- hospitalisation: results of a questionnaire-based study.BMC geriatrics · 2021Article
- COVID-19 and Acute Sarcopenia.Aging and disease · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundOlder adults are vulnerable to the effects of acute sarcopenia (acute muscle insufficiency) following hospitalisation. However, this condition remains poorly characterised to date. It is hypothesised that acute sarcopenia arises due to a combination of bed rest and inflammatory surge. This study aims to characterise changes in muscle quantity and function, determining which factors (clinical and biological) are most predictive, and how these relate to change in physical function at 13 weeks.
methodsThis study will include three groups of patients aged 70 years and older; patients undergoing elective colorectal surgery, patients admitted for emergency abdominal surgery, and patients admitted under general medicine with acute bacterial infections. Changes in muscle quantity (Bilateral Anterior Thigh Thickness with ultrasound and bioelectrical impedance analysis) and muscle function (muscle strength, physical performance) within 1 week of hospitalisation or surgery will be characterised, with follow-up of patients at 13 weeks. Physical function will be measured using the Patient Reported Outcome Measures Information System, and the Short Physical Performance Battery (or gait speed alone within 1 week of surgery). DISCUSSION: This study will fully characterise changes in muscle quantity and function in hospitalised older adults and enable risk stratification towards targeted interventions in clinical practice. The results of this study will inform further research involving interventions to ameliorate changes.
trial registrationClinicalTrials.gov Identifier: NCT03858192 ; Prospectively registered 28th February 2019.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.