Evidence map›Paper›PMID 32650647›Full record

ArticleThe British journal of radiology2020

Dosimetric study of whole-brain irradiation with high-energy photon beams for dose reduction to the scalp.

Masafumi Sawada, Etsuo Kunieda, Takeshi Akiba, Shigeto Kabuki, Ryuta Nagao, Tsuyoshi Fukuzawa, Yoshitsugu Matsumoto, Naoyuki Shigematsu

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Masafumi SawadaDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.ORCID http://orcid.org/0000-0002-2797-8469
Etsuo KuniedaDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Takeshi AkibaDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Shigeto KabukiDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Ryuta NagaoDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Tsuyoshi FukuzawaDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Yoshitsugu MatsumotoDepartment of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Naoyuki ShigematsuDepartment of Radiation Oncology, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
Tokai University · JPKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficiency of high-energy photons for mitigating alopecia due to whole-brain irradiation (WBRT).

methodsPlanning CT data from 10 patients who received WBRT were collected. We prepared 4 WBRT plans that used 6 or 15 MV photon beams, with or without use of a field-in-field (FiF) technique, and compared outcomes using a treatment planning system. The primary outcome was dose parameters to the scalp, including the mean dose, maximum dose, and dose received to 50% scalp(D50%). Secondary outcomes were minimum dose to the brain surface.

resultsUsing FiF, the mean doses were 24.4-26.0 and 22.4-24.1 Gy, and the maximum doses were 30.5-32.1 and 28.5-30.8 Gy for 6 and 15 MV photon beams, respectively. Without FiF, the mean doses were 24.6-26.9 and 22.6-24.5 Gy, and the maximum doses were 30.8-34.6 and 28.6-32.4 Gy for 6 and 15 MV photon beams. The 15 MV plan resulted in a lower scalp dose for each dose parameter (

conclusionCompared with the 6 MV plan, the 15 MV plan achieved a lower scalp dose without impairing the brain surface dose. ADVANCES IN KNOWLEDGE: High-energy photon WBRT may mitigate alopecia of patients who receiving WBRT.

Indexed as

Radiotherapy DosageAlopeciaBrain NeoplasmsHumansPhotonsRadiometryRadiotherapy Planning, Computer-AssistedScalpTomography, X-Ray Computed

Identifiers

PMID32650647
PMCPMC7548379
OpenAlexW3041032060

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.