Evidence map›Paper›PMID 32650608›Full record

ReviewNanomaterials (Basel, Switzerland)2020

Antioxidant Functionalized Nanoparticles: A Combat against Oxidative Stress.

Harsh Kumar, Kanchan Bhardwaj, Eugenie Nepovimova, Kamil Kuča, Daljeet Singh Dhanjal, Sonali Bhardwaj, Shashi Kant Bhatia, Rachna Verma, Dinesh Kumar

Open access · goldAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 305 citations in OpenAlex.

  1. Green Synthesis and Characterization of SiOApplied biochemistry and biotechnology · 2026
    Article
  2. Review
  3. Article
  4. Anti-Hyperglycemic and Antioxidant Effects ofInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
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  8. Antioxidant Activity of SiOLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Harsh KumarSchool of Bioengineering & Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India.ORCID 0000-0002-5301-484X
Kanchan BhardwajSchool of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India.
Eugenie NepovimovaDepartment of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Kamil KučaDepartment of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.ORCID 0000-0001-9664-1109
Daljeet Singh DhanjalSchool of Biotechnology and Biosciences, Lovely Professional University, Phagwara 144411, Punjab, India.ORCID 0000-0003-4791-7388
Sonali BhardwajSchool of Biotechnology and Biosciences, Lovely Professional University, Phagwara 144411, Punjab, India.
Shashi Kant BhatiaBiotransformation and Biomaterials Laboratory, Department of Microbial Engineering, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-7688-6069
Rachna VermaSchool of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India.
Dinesh KumarSchool of Bioengineering & Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India.
Shoolini University · INLovely Professional University · INUniversity of Hradec Králové · CZKonkuk University · KR

Funding

UHK Faculty of Science VT2019-2021
6 · The paper itself

Abstract

Numerous abiotic stresses trigger the overproduction of reactive oxygen species (ROS) that are highly toxic and reactive. These ROS are known to cause damage to carbohydrates, DNA, lipids and proteins, and build the oxidative stress and results in the induction of various diseases. To resolve this issue, antioxidants molecules have gained significant attention to scavenge these free radicals and ROS. However, poor absorption ability, difficulty in crossing the cell membranes and degradation of these antioxidants during delivery are the few challenges associated with both natural and synthetic antioxidants that limit their bioavailability. Moreover, the use of nanoparticles as an antioxidant is overlooked, and is limited to a few nanomaterials. To address these issues, antioxidant functionalized nanoparticles derived from various biological origin have emerged as an important alternative, because of properties like biocompatibility, high stability and targeted delivery. Algae, bacteria, fungi, lichens and plants are known as the producers of diverse secondary metabolites and phenolic compounds with extraordinary antioxidant properties. Hence, these compounds could be used in amalgamation with biogenic derived nanoparticles (NPs) for better antioxidant potential. This review intends to increase our knowledge about the antioxidant functionalized nanoparticles and the mechanism by which antioxidants empower nanoparticles to combat oxidative stress.

Indexed as

antioxidantsbiological nano-antioxidantsnanoparticlesoxidative stress

Identifiers

PMID32650608
PMCPMC7408424
OpenAlexW3041878535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.