Evidence map›Paper›PMID 32650518›Full record

Trial reportMedicina (Kaunas, Lithuania)2020

Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial.

Jannis Kountouras, Emmanuel Gavalas, Apostolis Papaefthymiou, Ioannis Tsechelidis, Stergios A Polyzos, Serhat Bor, Mircea Diculescu, Κhaled Jadallah, Mazurek Tadeusz, Tarkan Karakan and 8 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06268964 (Comparative Effect of Trimebutine and Probiotics on Functional Abdominal Pain Disorders), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06268964 phase1 / phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Comparative Effect of Trimebutine and Probiotics on Functional Abdominal Pain Disorders (FAPD) in Children: Randomized Clinical Trial (RCT)

TypeinterventionalSponsorUniversidad de ColimaRan2024 to 2025Enrolled82ConditionsFunctional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Irritable Bowel Syndrome Variant of ChildhoodArmsTrimebutine, Lactobacillus rhamnosus, Placebo
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Impact ofJournal of neurogastroenterology and motility · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 6 countries.

Jannis KountourasSecond Medical Clinic, School of Medicine, Aristotle University of Thessaloniki, Ippokration Hospital, 54642 Thessaloniki, Macedonia, Greece.
Emmanuel GavalasSecond Medical Clinic, School of Medicine, Aristotle University of Thessaloniki, Ippokration Hospital, 54642 Thessaloniki, Macedonia, Greece.
Apostolis PapaefthymiouSecond Medical Clinic, School of Medicine, Aristotle University of Thessaloniki, Ippokration Hospital, 54642 Thessaloniki, Macedonia, Greece.ORCID 0000-0002-3563-4973
Ioannis TsechelidisSecond Medical Clinic, School of Medicine, Aristotle University of Thessaloniki, Ippokration Hospital, 54642 Thessaloniki, Macedonia, Greece.
Stergios A PolyzosSecond Medical Clinic, School of Medicine, Aristotle University of Thessaloniki, Ippokration Hospital, 54642 Thessaloniki, Macedonia, Greece.
Serhat BorDivision of Gastroenterology, Ege University School of Medicine, 35330 Izmir, Turkey.
Mircea DiculescuGastroenterology and Hepatology Department, Clinic Fundeni Institute, 4204003 Bucharest, Romania.
Κhaled JadallahDepartment of Internal Medicine, King Abdullah University Hospital, 22110 Irbid, Jordan.
Mazurek TadeuszMedicor Centrum, ul. Jabłoskiego 2/4 35-068 Rzeszów, Poland.
Tarkan KarakanDepartment of Gastroenterology, Gazi University School of Medicine, 06560 Ankara, Turkey.
Αnna BochenekCentrum Badawcze Wspolczesnej Terapii, 02679 Warszawa, Poland.
Jerzy RozciechaLexMedica, Rudolfa Weigla 12, Krzyki, 53114 Wrocław, Poland.
Piotr DabrowskiDepartment of Rheumatology of Clinical Hospital 2, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland.
Zeno SparchezThird Medical Clinic, University of Medicine and Pharmacy, Croitorilor Street no.19-21, 400162 Cluj-Napoca, Romania.
Orhan SezginMersin University, Faculty of Medicine, Department of Gastroenterology, 33343 Mersin, Turkey.
Macit GültenDepartment of Gastroenterology, Uludag University, 16059 Bursa, Turkey.
Niazy Abu FarsakhDepartment of Internal Medicine, King Abdullah University Hospital, 22110 Irbid, Jordan.
Michael DoulberisSecond Medical Clinic, School of Medicine, Aristotle University of Thessaloniki, Ippokration Hospital, 54642 Thessaloniki, Macedonia, Greece.ORCID 0000-0002-0396-5081
Aristotle University of Thessaloniki · GRKing Abdullah University Hospital · JOBursa Uludağ Üni̇versi̇tesi̇ · TREge University · TRGazi University · TRInstitutul Clinic Fundeni · ROIuliu Hațieganu University of Medicine and Pharmacy · ROMersin Üniversitesi · TRUniversity of Rzeszów · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultDouble-Blind MethodDyspepsiaFemaleGastrointestinal AgentsGreeceHumansJordanMaleMiddle AgedPlacebosPolandProspective StudiesRomaniaStatistics, NonparametricTrimebutineGastrointestinal AgentsPlacebosTrimebutinefunctional dyspepsiagastrointestinal functiongastrointestinal motilitytrimebutine maleate

Identifiers

PMID32650518
PMCPMC7404657
OpenAlexW3041017001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.