ArticleInternational journal of molecular sciences2020
Simultaneous FTIR and Raman Spectroscopy in Endometrial Atypical Hyperplasia and Cancer.
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- New insights on collagen structural organization and spatial distribution around dental implants: a comparison between machined and laser-treated surfaces.Journal of translational medicine · 2024Trial
- Decoding the Endometriosis-Associated Infertility Microenvironment: A Review of FTIR and Raman Spectroscopic Insights into Follicular Fluid.Current issues in molecular biology · 2026Review
- The multifaceted role of hair as a biospecimen: recent advances in precision medicine and forensic science.Experimental & molecular medicine · 2025Review
- Detecting metabolic signatures in endometrial cancer: potential applications of Raman spectroscopy.Future oncology (London, England) · 2025Review
- Infrared and Raman spectroscopy of blood plasma for rapid endometrial cancer detection.British journal of cancer · 2025Article
- Detection of serum composition in pediatric inflammatory multisystem syndrome associated with SARS-CoV-2 and the response for the treatment by FTIR.Scientific reports · 2025Article
- Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids.mSystems · 2025Article
- Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders.Expert reviews in molecular medicine · 2024Review
- Advancements in medical research: Exploring Fourier Transform Infrared (FTIR) spectroscopy for tissue, cell, and hair sample analysis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Review
- Infrared Spectroscopy in Gynecological Oncology: A Comprehensive Review of Diagnostic Potentials and Challenges.International journal of molecular sciences · 2024Review
- Comparative analysis of porcine-uterine decellularization for bioactive-molecule preservation and DNA removal.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- The emerging applications and advancements of Raman spectroscopy in pediatric cancers.Frontiers in oncology · 2023Review
- Altered type I collagen networking in osteoporotic human femoral head revealed by histomorphometric and Fourier transform infrared imaging correlated analyses.BioFactors (Oxford, England) · 2022Article
- Vibrational Biospectroscopy: An Alternative Approach to Endometrial Cancer Diagnosis and Screening.International journal of molecular sciences · 2022Review
- Review
- Article
- Spectroscopic evaluation of carcinogenesis in endometrial cancer.Scientific reports · 2021Article
- Using the Method of "Optical Biopsy" of Prostatic Tissue to Diagnose Prostate Cancer.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Currently, endometrial carcinoma (EC) is the most common genital cancer in high-income countries. Some types of endometrial hyperplasia (EH) may be progressing to this malignancy. The diagnosis of EC and EH is based on time consuming histopathology evaluation, which is subjective and causes discrepancies in reassessment. Therefore, there is a need to create methods of objective evaluation allowing the diagnosis of early changes. The study aimed to simultaneously asses Fourier Transform Infrared (FTIR) and Raman spectroscopy combined with multidimensional analysis to identify the tissues of endometrial cancer, atypical hyperplasia and the normal control group, and differentiate them. The results of FTIR and Raman spectroscopy revealed quantitative and qualitative changes in the nucleic acid and protein in the groups of cancer and atypical hyperplasia, in comparison with the control group. Changes in the lipid region were also observed in Raman spectra. Pearson correlation coefficient demonstrated a statistically significant correlation between Raman spectra for the cancer and atypical hyperplasia groups (0.747,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.