Evidence map›Paper›PMID 32650393›Full record

ArticleMolecules (Basel, Switzerland)2020

X6: A Novel Antibody for Potential Use in Gluten Quantification.

Aleksandrina Shatalova, Ivan Shatalov, Yuri Lebedin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Aleksandrina ShatalovaFaculty of Food Biotechnologies and Engineering, ITMO University, Lomonosova Street, 9, 191002 St. Petersburg, Russia.ORCID 0000-0001-5891-7506
Ivan ShatalovELISA Development Department, XEMA Co., Ltd., Degtyarniy Lane, 8-10 St., 191144 Petersburg, Russian.ORCID 0000-0002-1676-5898
Yuri LebedinHead Office, XEMA Co., Ltd., 9-th Parkovaya str., 48, 105264 Moscow, Russian.
Elisa Development (Czechia) · CZITMO University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gliadin is a fraction of gluten, known to trigger celiac disease in susceptible people. To date, the life-long gluten-free diet is used for the prevention of this disease. Hence, methods for gluten control in foods are of significant importance. Being one of the most-used methods used for this purpose, ELISA should use high-affinity antibodies to gliadin peptides involved into celiac process. This study investigates the characteristics of a novel anti-gliadin antibody X6. We found the QXQPFPXP site to be a recognized epitope that provides specific binding of the antibody to cereal prolamins involved in celiac disease manifestation. A specificity study using immunoblotting shows the recognition of wheat, barley and rye proteins-as well as α-gliadin homologs from non-edible cereals (

Indexed as

AnimalsAntibodiesEdible GrainFemaleGliadinImmunoblottingMiceMice, Inbred BALB CAntibodiesGliadinceliac diseaseELISAepitope mappinggliadin

Identifiers

PMID32650393
PMCPMC7397180
OpenAlexW3040864185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.