Evidence map›Paper›PMID 32650380›Full record

ArticleJournal of clinical medicine2020

Association of Hypertensive Intracerebral Hemorrhage with Left Ventricular Hypertrophy on Transthoracic Echocardiography.

Lars-Peder Pallesen, Jenny Wagner, Dimitris Lambrou, Silke Braun, Matthias Weise, Alexandra Prakapenia, Jessica Barlinn, Timo Siepmann, Simon Winzer, Haidar Moustafa and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Idiopathic primary intraventricular hemorrhage and cerebral small vessel disease.International journal of stroke : official journal of the International Stroke Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Lars-Peder PallesenDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.ORCID 0000-0002-0084-4620
Jenny WagnerDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Dimitris LambrouDepartment of Medicine, University of Thessaly, 41500 Larissa, Greece.
Silke BraunMedical Clinic I, Dresden University of Technology, 01307 Dresden, Germany.
Matthias WeiseMedical Clinic III, Dresden University of Technology, 01307 Dresden, Germany.
Alexandra PrakapeniaDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Jessica BarlinnDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Timo SiepmannDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Simon WinzerDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Haidar MoustafaDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Hagen H KitzlerInstitute of Diagnostic and Interventional Neuroradiology, Dresden University of Technology, 01307 Dresden, Germany.
Kristian BarlinnDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Heinz ReichmannDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Volker PuetzDresden Neurovascular Center, Department of Neurology, Dresden University of Technology, 01307 Dresden, Germany.
Technische Universität Dresden · DEUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArterial hypertension is the most frequent cause for spontaneous intracerebral hemorrhage (sICH) and may also cause left ventricular hypertrophy (LVH). We sought to analyze whether hypertensive sICH etiology is associated with LVH.

methodsWe analyzed consecutive patients with sICH who were admitted to our tertiary stroke center during a four-year period and underwent transthoracic echocardiography (TTE) as part of the diagnostic work-up. We defined hypertensive sICH as typical localization of hemorrhage in patients with arterial hypertension and no other identified sICH etiology. We defined an increased end-diastolic interventricular septal wall thickness of ≥11 mm on TTE as a surrogate parameter for LVH.

resultsAmong 395 patients with sICH, 260 patients (65.8%) received TTE as part of their diagnostic work-up. The median age was 71 years (interquartile range (IQR) 17), 160 patients (61.5%) were male, the median baseline National Institute of Health Stroke Scale (NIHSS) score was 8 (IQR 13). Of these, 159 (61.2%) patients had a hypertensive sICH and 156 patients (60%) had LVH. In univariable (113/159 (71.1%) vs. 43/101 (42.6%); odds ratio (OR) 3.31; 95% confidence interval (CI

conclusionsIn patients with sICH, LVH is associated with hypertensive bleeding etiology. Performing TTE is meaningful for diagnosis of comorbidities and clarification of bleeding etiology in these patients. Future studies should include long-term outcome parameters and assess left ventricular mass as main indicator for LVH.

Indexed as

arterial hypertensionechocardiographyhypertensive cardiomyopathyintracerebral hemorrhageleft ventricular hypertrophy

Identifiers

PMID32650380
PMCPMC7408960
OpenAlexW3040693207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.