Evidence map›Paper›PMID 32650369›Full record

ArticleInternational journal of molecular sciences2020

Comparative Analysis, Structural Insights, and Substrate/Drug Interaction of CYP128A1 in

Nokwanda Samantha Ngcobo, Zinhle Edith Chiliza, Wanping Chen, Jae-Hyuk Yu, David R Nelson, Jack A Tuszynski, Jordane Preto, Khajamohiddin Syed

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Structure-Function Analysis of the EssentialInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Caseinolytic Proteins (Clp) in the GenusMolecules (Basel, Switzerland) · 2021
    Article
  6. In Silico Structural Modeling and Analysis of Interactions ofInternational journal of molecular sciences · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 7 countries.

Nokwanda Samantha NgcoboDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.ORCID 0000-0003-0840-5523
Zinhle Edith ChilizaDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Wanping ChenDepartment of Molecular Microbiology and Genetics, University of Göttingen, 37077 Göttingen, Germany.ORCID 0000-0002-6849-1972
Jae-Hyuk YuDepartment of Bacteriology, University of Wisconsin-Madison, 3155 MSB, 1550 Linden Drive, Madison, WI 53706, USA.ORCID 0000-0002-6530-8407
David R NelsonDepartment of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0003-0583-5421
Jack A TuszynskiDepartment of Physics and Department of Oncology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Jordane PretoUniversité Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69622 Lyon, France.
Khajamohiddin SyedDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.ORCID 0000-0002-1497-3570
University of Zululand · ZAUniversité Claude Bernard Lyon 1 · FRUniversity of Alberta · CAUniversity of Göttingen · DEUniversity of Tennessee Health Science Center · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytochrome P450 monooxygenases (CYPs/P450s) are well known for their role in organisms' primary and secondary metabolism. Among 20 P450s of the tuberculosis-causing

Indexed as

Bacterial ProteinsCytochrome P-450 Enzyme SystemGenome, BacterialMolecular Dynamics SimulationMultigene FamilyMycobacterium tuberculosisPharmaceutical PreparationsProtein BindingSecondary MetabolismBacterial ProteinsCytochrome P-450 Enzyme SystemPharmaceutical Preparationsazole drugsCYP128A1cytochrome P450 monooxygenenasesmenaquinonemolecular dynamic simulationsMycobacterium tuberculosis H37Rvtuberculosis

Identifiers

PMID32650369
PMCPMC7404182
OpenAlexW3038729907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.