ArticleEndoscopy2021
Defining the endoscopic ultrasound features of chronic pancreatitis in Asians: a multicenter validation study.
Article in Endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- EUS Shear Wave Measurement for Early Chronic Pancreatitis: A Retrospective Diagnostic Accuracy Study Using the 2019 JPS Criteria.Journal of clinical medicine · 2025Article
- Advancing the Diagnosis and Treatment of Early Chronic Pancreatitis Through Innovation in Imaging and Biomarker Profiling-A Narrative Review.Life (Basel, Switzerland) · 2025Review
- The Role of Endoscopic Ultrasound in Early Chronic Pancreatitis.Diagnostics (Basel, Switzerland) · 2024Review
- Proposal and Validation of New Diagnostic Criteria for Diagnostic Weights of Endoultrasonographic Findings for Early Chronic Pancreatitis.Journal of clinical medicine · 2023Article
- Impact of qualitative endoscopic ultrasonography on fatty pancreas at a referral medical center.JGH open : an open access journal of gastroenterology and hepatology · 2022Article
- Endoscopic Ultrasonography Findings of Early and Suspected Early Chronic Pancreatitis.Diagnostics (Basel, Switzerland) · 2020Review
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Authors and funding
22 authors at 18 institutions in 11 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough endoscopic ultrasound (EUS) features and criteria have been described in chronic pancreatitis, challenges remain with interoperator variability and ease of adoption. The aim of this study was to define and validate the EUS features of chronic pancreatitis in a multicenter prospective study in Asia.
methodThe study was divided into two parts: the first part was conducted to derive the EUS features of chronic pancreatitis with adequate interoperator agreement; the second was to prospectively evaluate these features in a multicenter cross-sectional study and determine the optimal combination of features for the diagnosis of chronic pancreatitis. Prospectively enrolled cases had standard internationally validated radiologic or histologic features of chronic pancreatitis, and controls were patients without chronic pancreatitis who underwent EUS examination.
resultsThe top six EUS features that had good interobserver agreement (mean kappa 0.73, range 0.60 - 0.90) were selected to be further evaluated in part II of the study. These included: hyperechoic foci with shadowing, lobularity with honeycombing, cysts, dilated main pancreatic duct, dilated side branches, and calculi in the main pancreatic duct. A total of 284 subjects (132 cases, 152 controls) were enrolled from 12 centers in Asia. All six features had high accuracy ranging from 63.3 % to 89.1 %. Two or more of these six EUS features accurately defined chronic pancreatitis (sensitivity 94.7 %, specificity 98.0 %), with an area under the receiver operating curve of 0.986.
conclusionThis multicenter Asian study characterized and defined the EUS features of chronic pancreatitis. This provides a useful tool in clinical practice and further research in pancreatic cancer surveillance.
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