Evidence map›Paper›PMID 32650287›Full record

ReviewCurrent opinion in insect science2020

Recent advances and future perspectives in vector-omics.

Austin Compton, Igor V Sharakhov, Zhijian Tu

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in insect science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Natural and Engineered Sex Ratio Distortion in Insects.Frontiers in ecology and evolution · 2022
    Article
  4. The regulatory genome of the malaria vectorNAR genomics and bioinformatics · 2021
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Austin ComptonDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061, United States; Fralin Life Science Institute, Virginia Tech, Blacksburg, VA 24061, United States.
Igor V SharakhovFralin Life Science Institute, Virginia Tech, Blacksburg, VA 24061, United States; Department of Entomology, Virginia Tech, Blacksburg, VA 24061, United States; The Interdisciplinary PhD Program in Genetics, Bioinformatics, and Computational Biology, Virginia Tech, Blacksburg, VA 24061, United States; Department of Genetics and Cell Biology, Tomsk State University, Tomsk 634050, Russia.
Zhijian TuDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061, United States; Department of Entomology, Virginia Tech, Blacksburg, VA 24061, United States; The Interdisciplinary PhD Program in Genetics, Bioinformatics, and Computational Biology, Virginia Tech, Blacksburg, VA 24061, United States. Electronic address: jaketu@vt.edu.
Virginia Tech · USNational Research Tomsk State University · RU

Funding

Mechanism and application of male determination in aedine mosquitoesR01AI123338 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2016 to 2020
$2.9M
Guy1-conferred female lethality: mechanism and application for mosquito controlR01AI121284 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2016 to 2020
$2.0M
Improving genome assemblies for species of the Anopheles gambiae complexR21AI135298 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SHARAKHOV, IGOR V · 2018 to 2019
$440k
Y chromosome genes in Anopheles mosquitoesR21AI133571 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2017 to 2018
$427k
Comparative genome mapping of the Anopheles species clusterR21AI099528 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SHARAKHOV, IGOR V · 2014 to 2015
$419k
NIAID NIH HHS R01 AI121284NIAID NIH HHS R01 AI123338NIAID NIH HHS R21 AI099528NIAID NIH HHS R21 AI133571NIAID NIH HHS R21 AI135298
6 · The paper itself

Abstract

We have reviewed recent progress and the remaining challenges in vector-omics. We have highlighted several technologies and applications that facilitate novel biological insights beyond achieving a reference-quality genome assembly. Among other topics, we have discussed the applications of chromatin conformation capture, chromatin accessibility assays, optical mapping, full-length RNA sequencing, single cell RNA analysis, proteomics, and population genomics. We anticipate that we will witness a great expansion in vector-omics research not only in its application in a broad range of species, but also its ability to uncover novel genetic elements and tackle previously inaccessible regions of the genome. It is our hope that the continued innovation in device portability, cost reduction, and informatics support will in the foreseeable future bring vector-omics to every vector laboratory and field station in the world, which will have an unparalleled impact on basic research and the control of vector-borne infectious diseases.

Indexed as

Genome, InsectAnimalsGenomicsInsectaInsect Vectors

Identifiers

PMID32650287
PMCPMC8041138
OpenAlexW3030094046

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.