Autophagy in preeclampsia: A new target?

Denise C Cornelius, Kedra Wallace

Abstract readComment

In one paragraph

Article in EBioMedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

The pathophysiology of pre-eclampsia.Nature reviews. Nephrology · 2026
Review
Cystatin 6 (CST6) and Legumain (LGMN) are potential mediators in the pathogenesis of preeclampsia.Scientific reports · 2025
Article
Autophagy-related biomarkers in preeclampsia: the underlying mechanism, correlation to the immune microenvironment and drug screening.BMC pregnancy and childbirth · 2024
Article
The Role of Sirtuin-1 (SIRT1) in the Physiology and Pathophysiology of the Human Placenta.International journal of molecular sciences · 2023
Review
Calcitonin gene-related peptide protects from soluble fms-like tyrosine kinase-1-induced vascular dysfunction in a preeclampsia mouse model.Frontiers in physiology · 2023
Article
Placenta autophagy is closely associated with preeclampsia.Aging · 2022
Article
SIRT1: A Novel Protective Molecule in Pre-eclampsia.International journal of medical sciences · 2022
Review

4 · The record

Corrections and comments

Comment on
The Inhibition of Protein Kinase C β Contributes to the Pathogenesis of Preeclampsia by Activating Autophagy.2020

5 · Who and what money

Authors and funding

2 authors.

Denise C CorneliusDepartments of Emergency Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, United States; Departments of Pharmacology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, United States.

Kedra WallaceDepartments of Obstetrics & Gynecology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, United States; Departments of Neurobiology & Anatomical Sciences, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, United States. Electronic address: kwallace2@umc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pre-EclampsiaAutophagyFemaleHumansPlacentaPregnancy

Identifiers

PMID32650269

DOI10.1016/j.ebiom.2020.102864

PMCPMC7341341

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.