Evidence map›Paper›PMID 32650029›Full record

ArticleNeurochemistry international2020

Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression.

Zila Martinez-Lozada, Michael B Robinson

Open access · greenAbstract read
In one paragraph

Article in Neurochemistry international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zila Martinez-LozadaDepartments of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA, 19104-4318.
Michael B RobinsonDepartments of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA, 19104-4318; Systems Pharmacology and Translational Therapeutics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, 19104-4318, USA. Electronic address: robinson@pennmedicine.upenn.edu.
Children's Hospital of Philadelphia · US

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ERIC D MARSH, ROBERT Thomas SCHULTZ · 2021 to 2026
$9.2M
The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBINSON, MICHAEL BYRNE · 2016 to 2020
$6.3M
Regulation of glutamate transport in astrocyte subtypes and in ALSR01NS092067 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBINSON, MICHAEL BYRNE, ROTHSTEIN, JEFFREY D · 2015 to 2019
$2.3M
NICHD NIH HHS P50 HD105354NICHD NIH HHS U54 HD086984NINDS NIH HHS R01 NS092067
6 · The paper itself

Abstract

Astrocytes have diverse functions that are supported by their anatomic localization between neurons and blood vessels. One of these functions is the clearance of extracellular glutamate. Astrocytes clear glutamate using two Na

Indexed as

AnimalsAstrocytesCell CommunicationCells, CulturedCoculture TechniquesEndothelial CellsExcitatory Amino Acid Transporter 2FemaleGene Expression RegulationMaleMiceRatsRats, Sprague-DawleyExcitatory Amino Acid Transporter 2Slc1a2 protein, ratAstrocytesBlood-brain barrierEndotheliaGLASTGLT-1Notch

Identifiers

PMID32650029
PMCPMC7484234
OpenAlexW3042056420

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.