ArticlePloS one2020
Prevalence and risk factors for asthma, rhinitis, eczema, and atopy among preschool children in an Andean city.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Operational definitions of paediatric asthma used in epidemiological studies: A systematic review.Journal of global health · 2021Pooled it
- The Burden of Early-Childhood Atopic Disease: Prevalence and Risk Factors for Allergic Rhinitis in an Informal Settlement in South Africa.Children (Basel, Switzerland) · 2026Article
- Factors Influencing Asthma in Children at Early Childhood Development Centres in a Densely Populated Urban Informal Township in Gauteng Province, South Africa.Children (Basel, Switzerland) · 2026Article
- A Study Protocol to Assess the Association Between Ambient Air Pollution and Asthma and Other Respiratory Health Outcomes Amongst Children Below 5 Years of Age in Alexandra Township's Early Childhood Development Centers, Johannesburg.Methods and protocols · 2025Article
- Prevalence of Asthma, Allergic Rhinitis, and Eczema in Schoolchildren From Huambo, Angola: A Cross-Sectional Study.Health science reports · 2025Article
- Systematic review of existing literature regarding the prevalence of pediatric atopic dermatitis in Honduras.JAAD international · 2024Review
- Mother's smoking habits affects IL10 methylation but not asthma in Ecuadorian children.Molecular genetics & genomic medicine · 2024Article
- Pediatric asthma and altitude: a complex interplay between different environmental factors.Italian journal of pediatrics · 2024Review
- Assessing the prevalence and severity of asthma, rhinitis, and eczema among schoolchildren (6-7 and 13-14 years old) in Khuzestan, Iran: a cross-sectional survey.BMC pediatrics · 2022Article
- Asthma, rhinitis and eczema symptoms in Quito, Ecuador: a comparative cross-sectional study 16 years after ISAAC.BMJ open respiratory research · 2021Article
- Patterns of allergic sensitization and factors associated with emergence of sensitization in the rural tropics early in the life course: findings of an Ecuadorian birth cohort.Frontiers in allergy · 2021Article
- Risk factors for allergic diseases: a cross-sectional survey of 9,501 Chinese preschool-aged children.Translational pediatrics · 2021Article
- Socio-demographics and asthma prevalence, management, and outcomes among children 1-11 years of age in California.Global health research and policy · 2021Article
- Trends in hospital admissions and mortality rates for asthma in Ecuador: a joinpoint regression analysis of data from 2000 to 2018.BMJ open respiratory research · 2021Article
- Environmental risk factor assessment for major respiratory disorders in metropolitan cities of India using VIIRS Suomi Aerosol data and Google Trends.Environmental sustainability (Singapore) · 2021Article
- Correction: Prevalence and risk factors for asthma, rhinitis, eczema, and atopy among preschool children in an Andean city.PloS one · 2020Article
- Prevalence and associated factors for asthma in adults in Quito: a cross-sectional study.Colombia medica (Cali, Colombia)Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLimited data are available on prevalence and associated risk factors for atopy and allergic diseases from high-altitude urban settings in Latin America.
objectiveTo estimate the prevalence of atopy, asthma, rhinitis, and eczema, and associations with relevant risk factors in preschool children in the Andean city of Cuenca.
methodsA cross-sectional study was undertaken using a representative sample of 535 children aged 3-5 years attending 30 nursery schools in the city of Cuenca, Ecuador. Data on allergic diseases and risk factors were collected by parental questionnaire. Atopy was measured by skin prick test (SPT) reactivity to a panel of relevant aeroallergens. Associations between risk factors and the prevalence of atopy and allergic diseases were estimated using multivariable logistic regression.
resultsAsthma symptoms were reported for 18% of children, rhinitis for 48%, and eczema for 28%, while SPT reactivity was present in 33%. Population fractions of asthma, rhinitis, and eczema attributable to SPT were 3.4%, 7.9%, and 2.9%, respectively. In multivariable models, an increased risk of asthma was observed among children with a maternal history of rhinitis (OR 1.85); rhinitis was significantly increased in children of high compared to low socioeconomic level (OR 2.09), among children with a maternal history of rhinitis (OR 2.29) or paternal history of eczema (OR 2.07), but reduced among children attending daycare (OR 0.64); eczema was associated with a paternal history of eczema (OR 3.73), and SPT was associated with having a dog inside the house (OR 1.67).
conclusionsA high prevalence of asthma, rhinitis, and eczema symptoms were observed among preschool children in a high-altitude Andean setting. Despite a high prevalence of atopy, only a small fraction of symptoms was associated with atopy. Parental history of allergic diseases was the most consistent risk factor for symptoms in preschool children.
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