Evidence map›Paper›PMID 32649417›Full record

ArticleJournal of the Chinese Medical Association : JCMA2020

The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study.

Hsin-Fu Yeh, Tsai-Feng Li, Cheng-Hung Tsai, Pei-Wen Wu, Yi-Hsiu Huang, William J Huang, Fun-Jou Chen, Shinn-Jang Hwang, Fang-Pey Chen, Ta-Peng Wu

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Chinese Medical Association : JCMA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hsin-Fu YehDepartment of Family Medicine, St. Martin De Porres Hospital, Chiayi, Taiwan, ROC.
Tsai-Feng LiCenter for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Cheng-Hung TsaiCenter for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Pei-Wen WuCenter for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yi-Hsiu HuangDepartment of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
William J HuangDepartment of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Fun-Jou ChenSchool of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC.
Shinn-Jang HwangSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Fang-Pey ChenInstitute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Ta-Peng WuCenter for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Taipei Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current Western medicine treatment options for benign prostatic hyperplasia (BPH) have various degrees of documented effectiveness. However, the uses of these interventions are limited to specific patient populations or have certain side effects that interfere with patient quality of life. This study evaluated the clinical effects of a Chinese herbal medicine (CHM) on patients with BPH.

methodsThis was a single-arm pilot study. Twenty BPH patients were enrolled, and they were required to take the investigated CHM three times a day for 8 weeks, along with their Western medicine. Patients returned to clinics as scheduled and completing international prostate symptoms scores (IPSS), aging male symptoms score, international index of erectile function, and body constitution questionnaire of traditional Chinese medicine. Uroflowmetry and sonography were also applied to evaluate the changes in urinary velocity and post-voiding residual urine volume from the baseline to the end of the study.

resultsThe mean IPSS total score was significantly decreased by 2.5 points after 8 weeks of treatment with the CHM (from 17.5 to 15.0, p = 0.03). The mean IPSS voiding subscore was decreased by 1.7 points (from 10.1 to 8.4, p = 0.02), and the mean incomplete emptying subscore was decreased by 0.8 points (from 2.9 to 2.1, p = 0.02), with both decreases being statistically significant. A descending trend in the post-voiding residual urine volume was also observed (from 52.9 to 30.8 mL, p = 0.07).

conclusionThis trial indicated that the add-on CHM treatment (VGHBPH0) might be a potential treatment for improving the lower urinary tract symptoms of BPH patients.

Indexed as

AgedAged, 80 and overDrugs, Chinese HerbalHumansMaleMiddle AgedPilot ProjectsProstatic HyperplasiaDrugs, Chinese Herbal

Identifiers

PMID32649417
PMCPMC7526580
OpenAlexW3041141742

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.