Evidence map›Paper›PMID 32649411›Full record

ArticleJournal of the Chinese Medical Association : JCMA2020

Better endovascular mechanical thrombectomy outcome in atrial fibrillation patients with acute ischemic stroke: A single-center experience.

Chun-Jen Lin, Chao-Bao Luo, Chun Chien, Feng-Chi Chang, Chung-Jung Lin, I-Hui Lee, Li-Chi Hsu, Chih-Ping Chung, Hung-Yu Liu, Nai-Fang Chi and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Chinese Medical Association : JCMA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Treatment with Manganese Porphyrin, MnTnBuOE-2-PyPPharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Chun-Jen LinNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chao-Bao LuoSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Chun ChienNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Feng-Chi ChangSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Chung-Jung LinSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
I-Hui LeeNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Li-Chi HsuNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chih-Ping ChungNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Hung-Yu LiuNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Nai-Fang ChiNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chorng-Kuang HowSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Shuu-Jiun WangNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Wan-Yuo GuoSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Yung-Yang LinNeurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Taipei Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TWNational Taipei University · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndovascular thrombectomy (EVT) has become the standard treatment for acute ischemic stroke with large vessel occlusion. Atrial fibrillation (AF) is one of the major causes. However, the impact of AF on the treatment has not yet been clearly discussed. This study is to evaluate the influence of AF on the outcomes of EVT in patients with acute ischemic stroke.

methodsData from our Stroke Registry Database from April 2015 to July 2018 were reviewed. Technical efficacy, functional, and safety outcomes were reported and compared between patients with and without AF. A multivariate logistic regression model was performed to identify the predictors of the good functional outcome.

resultsWe reviewed 83 eligible patients receiving EVT. Patients (51.8%) were eventually found to have AF. The substantial reperfusion rate (modified thrombolysis in cerebral infarction 2b-3) was 72.1% and 55.0% in patients with and without AF, respectively, inclusive of a learning curve (p = 0.12). The good functional outcome (90-day modified Rankin scale: 0 to 2) rate was 55.8% and 17.5% in patients with and without AF, respectively (p < 0.01). A multivariable logistic regression analysis showed that age <70 years, the substantial reperfusion, and the presence of AF were three significant predictors for a good functional outcome.

conclusionOur study showed that patients with AF responded significantly better to EVT than those without AF did. Intracranial atherosclerotic diseases in patients without AF which were especially refractory to EVT may contribute to the difference of the functional outcomes between the two groups.

Indexed as

AgedAged, 80 and overAtrial FibrillationEndovascular ProceduresFemaleHumansIschemic StrokeLogistic ModelsMaleMiddle AgedRetrospective StudiesThrombectomy

Identifiers

PMID32649411
PMCPMC12991653
OpenAlexW3040863884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.