Evidence map›Paper›PMID 32649311›Full record

ArticleAging2020

PGK1 inhibitor CBR-470-1 protects neuronal cells from MPP+.

Jinyu Zheng, Jian-Liang Zhu, Yufeng Zhang, Hao Zhang, Yu Yang, De-Rong Tang, Jian Sun

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jinyu ZhengDepartment of Neurosurgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
Jian-Liang ZhuDepartment of Emergency and Intensive Care Unit, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yufeng ZhangDepartment of Anesthesiology, Huai'an Maternity and Child Clinical College of Xuzhou Medical University, Huai'an, China.
Hao ZhangDepartment of Anesthesiology, Huai'an Maternity and Child Clinical College of Xuzhou Medical University, Huai'an, China.
Yu YangDepartment of Emergency and Intensive Care Unit, The Second Affiliated Hospital of Soochow University, Suzhou, China.
De-Rong TangDepartment of Thoracic Surgery, The Affiliated Huaian People's Hospital of Nanjing Medical University, Huai'an, China.
Jian SunDepartment of Anesthesiology, Huai'an Maternity and Child Clinical College of Xuzhou Medical University, Huai'an, China.
Xuzhou Medical College · CNNanjing Medical University · CNSecond Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurotoxin MPP

Indexed as

1-Methyl-4-phenylpyridiniumCell Line, TumorGene Knockout TechniquesHumansKelch-Like ECH-Associated Protein 1MitochondriaNeuroprotective AgentsNeurotoxicity SyndromesNF-E2-Related Factor 2Phosphoglycerate KinaseRNA, Small InterferingSignal Transduction1-Methyl-4-phenylpyridiniumKEAP1 protein, humanKelch-Like ECH-Associated Protein 1Neuroprotective AgentsNFE2L2 protein, humanNF-E2-Related Factor 2PGK1 protein, humanPhosphoglycerate KinaseRNA, Small InterferingCBR-470-1MPP+Nrf2PGK1SH-SY5Y cells

Identifiers

PMID32649311
PMCPMC7377839
OpenAlexW3042019625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.