Evidence map›Paper›PMID 32649262›Full record

ArticleInternational journal of immunopathology and pharmacology

Don't forget ototoxicity during the SARS-CoV-2 (Covid-19) pandemic!

Andrea Ciorba, Virginia Corazzi, Piotr Henryk Skarżyński, Magdalena B Skarżyńska, Chiara Bianchini, Stefano Pelucchi, Stavros Hatzopoulos

Abstract readLetter
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. SARS-CoV-2 (COVID-19) and audio-vestibular disorders.International journal of immunopathology and pharmacology
    Pooled it
  2. Review
  3. Article
  4. Impact of COVID-19 Medication (Favipiravir and Hydroxychloroquine) on High Frequency Hearing.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  5. Study of Hearing Status in COVID-19 Patients: A Multicentered Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  6. Slight High-Frequency Hearing Loss, Effect of COVID-19 or Hydroxychloroquine Usage?Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2022
    Article
  7. Review
  8. Article
  9. ENT symptoms in acute COVID-19: a narrative review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2022
    Review
  10. Mild and moderate COVID-19 disease does not affect hearing function permanently: a cross-sectional study ınvolving young and middle-aged healthcare givers.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea CiorbaENT & Audiology Department, University Hospital of Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0003-3455-2295
Virginia CorazziENT & Audiology Department, University Hospital of Ferrara, Ferrara, Italy.
Piotr Henryk SkarżyńskiInstitute of Physiology and Pathology of Hearing, Warsaw, Poland.
Magdalena B SkarżyńskaInstitute of Physiology and Pathology of Hearing, Warsaw, Poland.
Chiara BianchiniENT & Audiology Department, University Hospital of Ferrara, Ferrara, Italy.
Stefano PelucchiENT & Audiology Department, University Hospital of Ferrara, Ferrara, Italy.
Stavros HatzopoulosENT & Audiology Department, University Hospital of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim of this communication is to remind clinical professionals to be aware of ototoxic side effects of several specific drugs proposed for the treatment of the new virus SARS-CoV-2 (Covid-19). In particular, chloroquine and hydroxychloroquine, azithromycin, as well as antiviral drugs such as remdesivir, favipiravir and lopinavir can all present potential ototoxic side effects. The data in the literature do not offer specific information on their potential synergetic effects nor on their interactions.

Indexed as

Drug MonitoringOtotoxicityAntimalarialsAntiviral AgentsAzithromycinCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentHearing DisordersHearing TestsHumansPandemicsPneumonia, ViralAntimalarialsAntiviral AgentsAzithromycinchloroquinefavipiravirhydroxychloroquinelopinavirototoxicityremdesivirSARS-CoV-2 (Covid-19) pandemic

Identifiers

PMID32649262
PMCPMC7357052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.