Evidence map›Paper›PMID 32648823›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2020

In vivo [U-

Moritz Schnelle, Mei Chong, Anna Zoccarato, Manar Elkenani, Greta Jane Sawyer, Gerd Hasenfuss, Christian Ludwig, Ajay M Shah

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Glutamine Metabolism in Cardiac Hypertrophy.Reviews in cardiovascular medicine · 2026
    Review
  2. Article
  3. Late-Stage Phenylation From [Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  4. Targeted Metabolomic Methods forJournal of proteome research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Cardio-Onco-Metabolism - Metabolic vulnerabilities in cancer and the heart.Journal of molecular and cellular cardiology · 2022
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. In vivoCurrent opinion in biotechnology · 2021
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Moritz SchnelleKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences, London, United Kingdom.
Mei ChongKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences, London, United Kingdom.
Anna ZoccaratoKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences, London, United Kingdom.
Manar ElkenaniKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences, London, United Kingdom.
Greta Jane SawyerKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences, London, United Kingdom.
Gerd HasenfussDepartment of Cardiology and Pneumology, University Medical Center Goettingen, Goettingen, Germany.ORCID 0000-0002-5942-361X
Christian LudwigInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, United Kingdom.ORCID 0000-0001-8901-6970
Ajay M ShahKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences, London, United Kingdom.
King's College London · GBGerman Centre for Cardiovascular Research · DEUniversity of Birmingham · GB

Funding

British Heart Foundation RG/13/11/30384British Heart Foundation RG/20/3/34823
6 · The paper itself

Abstract

Alterations in the metabolism of substrates such as glucose are integrally linked to the structural and functional changes that occur in the remodeling heart. Assessment of such metabolic changes under in vivo conditions would provide important insights into this interrelationship. We aimed to investigate glucose carbon metabolism in pressure-overload and volume-overload cardiac hypertrophy by using an in vivo [U-

Indexed as

Energy MetabolismVentricular Function, LeftVentricular RemodelingAnimalsBlood GlucoseCarbon IsotopesCitric Acid CycleDisease Models, AnimalGlycolysisHypertrophy, Left VentricularKineticsLactic AcidMagnetic Resonance SpectroscopyMaleMice, Inbred C57BLMyocardiumBlood GlucoseCarbon IsotopesLactic Acid[13C]glucosecardiac metabolismin vivomousepressure and volume overload

Identifiers

PMID32648823
PMCPMC7473922
OpenAlexW3040960259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.